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• W2050688889 abstract "The most modifiable risk factor for post-transplant lymphoproliferative disease (PTLD) is the type and dose of induction and maintenance immunosuppressive therapy. It is challenging to identify the contribution of a single agent such as rabbit antithymocyte globulin (rATG) in the setting of multidrug therapy. Registry analyses can be helpful but are limited by methodological restrictions and inclusion of historical patient cohorts. These are typically from eras when rATG dosing was markedly higher than current dosing (e.g. total dose 14 mg/kg versus 6 mg/kg now), accompanied by higher exposure to maintenance therapies, and often an absence of antiviral prophylaxis. The largest registry analysis to assess rATG specifically found no risk of PTLD after kidney transplantation, but conflicting results have been reported, highlighting the difficulty of interpreting this type of analysis. The relative rarity of PTLD means that individually controlled trials are underpowered to assess its occurrence, but the available data do not suggest an effect of rATG. A pooled analysis of data from studies of rATG induction in kidney and heart transplantation found the incidence of PTLD to be comparable to published reports in the overall transplant population. Data on the effect of rATG dose are inconclusive, but in patients receiving antiviral prophylaxis it does not appear to be influential. Nevertheless, it would seem reasonable to employ the lowest dose of rATG compatible with effective induction, particularly in EBV-seronegative recipients and other high-risk groups such as heart-lung transplant recipients. Overall, the risk of PTLD following rATG induction therapy with modern dosing regimens and under current management conditions appears unlikely to make an important contribution to the risk:benefit balance." @default.
• W2050688889 created "2016-06-24" @default.
• W2050688889 creator A5036557921 @default.
• W2050688889 creator A5049546637 @default.
• W2050688889 date "2015-06-01" @default.
• W2050688889 modified "2023-09-25" @default.
• W2050688889 title "Rabbit antithymocyte globulin induction and risk of post-transplant lymphoproliferative disease in adult and pediatric solid organ transplantation: An update" @default.
• W2050688889 cites W130307429 @default.
• W2050688889 cites W1518299472 @default.
• W2050688889 cites W1555918218 @default.
• W2050688889 cites W1569506958 @default.
• W2050688889 cites W1586534080 @default.
• W2050688889 cites W1620859194 @default.
• W2050688889 cites W1765070428 @default.
• W2050688889 cites W1925602349 @default.
• W2050688889 cites W1949775700 @default.
• W2050688889 cites W1964226694 @default.
• W2050688889 cites W1975501972 @default.
• W2050688889 cites W1979589362 @default.
• W2050688889 cites W1980998626 @default.
• W2050688889 cites W1981283210 @default.
• W2050688889 cites W1981435382 @default.
• W2050688889 cites W1986339166 @default.
• W2050688889 cites W1989488484 @default.
• W2050688889 cites W1991477119 @default.
• W2050688889 cites W1991743078 @default.
• W2050688889 cites W1998407875 @default.
• W2050688889 cites W1999298846 @default.
• W2050688889 cites W2000525727 @default.
• W2050688889 cites W2000531481 @default.
• W2050688889 cites W2002831593 @default.
• W2050688889 cites W2011204410 @default.
• W2050688889 cites W2012727366 @default.
• W2050688889 cites W2013078073 @default.
• W2050688889 cites W2014752904 @default.
• W2050688889 cites W2015101712 @default.
• W2050688889 cites W2018100390 @default.
• W2050688889 cites W2022720972 @default.
• W2050688889 cites W2025790500 @default.
• W2050688889 cites W2025932421 @default.
• W2050688889 cites W2031411652 @default.
• W2050688889 cites W2031832264 @default.
• W2050688889 cites W2032596326 @default.
• W2050688889 cites W2035492842 @default.
• W2050688889 cites W2037926194 @default.
• W2050688889 cites W2043250502 @default.
• W2050688889 cites W2044215074 @default.
• W2050688889 cites W2044379313 @default.
• W2050688889 cites W2045224955 @default.
• W2050688889 cites W2049917853 @default.
• W2050688889 cites W2052036695 @default.
• W2050688889 cites W2052228881 @default.
• W2050688889 cites W2052712722 @default.
• W2050688889 cites W2055543492 @default.
• W2050688889 cites W2061649963 @default.
• W2050688889 cites W2069726523 @default.
• W2050688889 cites W2072651170 @default.
• W2050688889 cites W2075059327 @default.
• W2050688889 cites W2079830501 @default.
• W2050688889 cites W2088588216 @default.
• W2050688889 cites W2088807765 @default.
• W2050688889 cites W2091851863 @default.
• W2050688889 cites W2094352696 @default.
• W2050688889 cites W2096243799 @default.
• W2050688889 cites W2110758097 @default.
• W2050688889 cites W2116508491 @default.
• W2050688889 cites W2118511629 @default.
• W2050688889 cites W2119441823 @default.
• W2050688889 cites W2120711140 @default.
• W2050688889 cites W2131598459 @default.
• W2050688889 cites W2132737364 @default.
• W2050688889 cites W2135136335 @default.
• W2050688889 cites W2139241553 @default.
• W2050688889 cites W2140388899 @default.
• W2050688889 cites W2141316254 @default.
• W2050688889 cites W2144590996 @default.
• W2050688889 cites W2146779691 @default.
• W2050688889 cites W2151093173 @default.
• W2050688889 cites W2155953802 @default.
• W2050688889 cites W2156651430 @default.
• W2050688889 cites W2159704900 @default.
• W2050688889 cites W2167078188 @default.
• W2050688889 cites W2170783570 @default.
• W2050688889 cites W2326233113 @default.
• W2050688889 cites W2328308299 @default.
• W2050688889 cites W2775382379 @default.
• W2050688889 cites W2917955192 @default.
• W2050688889 doi "https://doi.org/10.1016/j.trim.2015.04.003" @default.
• W2050688889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25936966" @default.
• W2050688889 hasPublicationYear "2015" @default.
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