FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050800951> ?p ?o ?g. }

• W2050800951 endingPage "1432" @default.
• W2050800951 startingPage "1427" @default.
• W2050800951 abstract "From 1995 to 1996 about 15 people suspected of being overexposed to ionizing radiation were referred to the Institute for Nuclear Safety and Protection in Fontenay-aux-Roses, France, for investigation by chromosome aberration analysis. Biological estimates of accidental overexposure were first obtained by scoring radio-induced unstable structural chromosome aberrations (dicentrics, centric rings, and fragments) in peripheral blood lymphocytes. For dose estimates, the yield of these chromosomal aberrations observed in 500 metaphases was compared with the laboratory dose-response relationship established from human blood irradiated in vitro (gamma-rays, 60Co, 0.5 Gy/min). To extend the possibilities of detecting DNA damage from earlier exposures by visualizing stable chromosome aberrations, chromosome painting by fluorescence in situ hybridization (FISH painting) was developed using a cocktail of three composite whole human chromosome-specific DNA probes (numbers 2, 4, and 12). A laboratory calibration curve for scoring terminal and/or reciprocal translocations was established for the same radiation quality and dose rate as those used for conventional cytogenetics (gamma-rays, 60Co, 0.5 Gy/min). For dosimetry purposes, it was also important to verify whether FISH painting could be applied to each human blood sample assessed for conventional expertise. For each individual, 2000 metaphases were scored for the presence or absence of reciprocal and terminal translocations. We present here a comparison between the results obtained by the two technologies for each of the cases studied separately. We describe their similarities or differences and discuss the suitability of using FISH painting for routine expertise analysis." @default.
• W2050800951 created "2016-06-24" @default.
• W2050800951 creator A5017527972 @default.
• W2050800951 creator A5021084621 @default.
• W2050800951 creator A5029132812 @default.
• W2050800951 creator A5040113766 @default.
• W2050800951 creator A5059687911 @default.
• W2050800951 creator A5075235854 @default.
• W2050800951 date "1997-12-01" @default.
• W2050800951 modified "2023-10-04" @default.
• W2050800951 title "Is FISH painting an appropriate biological marker for dose estimates of suspected accidental radiation overexposure? A review of cases investigated in France from 1995 to 1996." @default.
• W2050800951 cites W1986490537 @default.
• W2050800951 cites W2015125731 @default.
• W2050800951 cites W2025560566 @default.
• W2050800951 cites W2025912239 @default.
• W2050800951 cites W2034498138 @default.
• W2050800951 cites W2039529706 @default.
• W2050800951 cites W2042426488 @default.
• W2050800951 cites W2069644796 @default.
• W2050800951 cites W2079937000 @default.
• W2050800951 cites W2082713935 @default.
• W2050800951 cites W2085695808 @default.
• W2050800951 cites W2090974930 @default.
• W2050800951 cites W2102332749 @default.
• W2050800951 cites W2107615114 @default.
• W2050800951 cites W2108994753 @default.
• W2050800951 cites W2119447976 @default.
• W2050800951 cites W2141033510 @default.
• W2050800951 cites W2161325825 @default.
• W2050800951 doi "https://doi.org/10.1289/ehp.97105s61427" @default.
• W2050800951 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1469948" @default.
• W2050800951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9467056" @default.
• W2050800951 hasPublicationYear "1997" @default.
• W2050800951 type Work @default.
• W2050800951 sameAs 2050800951 @default.
• W2050800951 citedByCount "12" @default.
• W2050800951 countsByYear W20508009512014 @default.
• W2050800951 countsByYear W20508009512017 @default.
• W2050800951 countsByYear W20508009512018 @default.
• W2050800951 countsByYear W20508009512023 @default.
• W2050800951 crossrefType "journal-article" @default.
• W2050800951 hasAuthorship W2050800951A5017527972 @default.
• W2050800951 hasAuthorship W2050800951A5021084621 @default.
• W2050800951 hasAuthorship W2050800951A5029132812 @default.
• W2050800951 hasAuthorship W2050800951A5040113766 @default.
• W2050800951 hasAuthorship W2050800951A5059687911 @default.
• W2050800951 hasAuthorship W2050800951A5075235854 @default.
• W2050800951 hasBestOaLocation W20508009511 @default.
• W2050800951 hasConcept C104317684 @default.
• W2050800951 hasConcept C111337013 @default.
• W2050800951 hasConcept C121332964 @default.
• W2050800951 hasConcept C138626823 @default.
• W2050800951 hasConcept C174475383 @default.
• W2050800951 hasConcept C18231593 @default.
• W2050800951 hasConcept C185544564 @default.
• W2050800951 hasConcept C203014093 @default.
• W2050800951 hasConcept C2777542201 @default.
• W2050800951 hasConcept C2909208804 @default.
• W2050800951 hasConcept C2989005 @default.
• W2050800951 hasConcept C3017910909 @default.
• W2050800951 hasConcept C30481170 @default.
• W2050800951 hasConcept C505870484 @default.
• W2050800951 hasConcept C54355233 @default.
• W2050800951 hasConcept C71924100 @default.
• W2050800951 hasConcept C75088862 @default.
• W2050800951 hasConcept C86803240 @default.
• W2050800951 hasConceptScore W2050800951C104317684 @default.
• W2050800951 hasConceptScore W2050800951C111337013 @default.
• W2050800951 hasConceptScore W2050800951C121332964 @default.
• W2050800951 hasConceptScore W2050800951C138626823 @default.
• W2050800951 hasConceptScore W2050800951C174475383 @default.
• W2050800951 hasConceptScore W2050800951C18231593 @default.
• W2050800951 hasConceptScore W2050800951C185544564 @default.
• W2050800951 hasConceptScore W2050800951C203014093 @default.
• W2050800951 hasConceptScore W2050800951C2777542201 @default.
• W2050800951 hasConceptScore W2050800951C2909208804 @default.
• W2050800951 hasConceptScore W2050800951C2989005 @default.
• W2050800951 hasConceptScore W2050800951C3017910909 @default.
• W2050800951 hasConceptScore W2050800951C30481170 @default.
• W2050800951 hasConceptScore W2050800951C505870484 @default.
• W2050800951 hasConceptScore W2050800951C54355233 @default.
• W2050800951 hasConceptScore W2050800951C71924100 @default.
• W2050800951 hasConceptScore W2050800951C75088862 @default.
• W2050800951 hasConceptScore W2050800951C86803240 @default.
• W2050800951 hasIssue "suppl 6" @default.
• W2050800951 hasLocation W20508009511 @default.
• W2050800951 hasLocation W20508009512 @default.
• W2050800951 hasLocation W20508009513 @default.
• W2050800951 hasLocation W20508009514 @default.
• W2050800951 hasOpenAccess W2050800951 @default.
• W2050800951 hasPrimaryLocation W20508009511 @default.
• W2050800951 hasRelatedWork W1968542164 @default.
• W2050800951 hasRelatedWork W1975964136 @default.
• W2050800951 hasRelatedWork W2042227098 @default.
• W2050800951 hasRelatedWork W2045708821 @default.
• W2050800951 hasRelatedWork W2180015301 @default.
• W2050800951 hasRelatedWork W2363246267 @default.
• W2050800951 hasRelatedWork W2363435430 @default.

• next