Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050803707> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2050803707 endingPage "114" @default.
- W2050803707 startingPage "110" @default.
- W2050803707 abstract "Background Insulin-like growth factor-1 (IGF-1) has specific effects on axonal growth and myelination, low CSF IGF-1 levels being found in some severe neurologic diseases. We studied the levels of CSF IGF-1 and IGF binding protein-2 (IGFBP-2) in children with ALL to find out whether these levels correlated with any of the neurological deficits observed. Methods IGF-1 and IGFBP-2 levels were prospectively measured by radioimmunoassay in the CSF of 14 children with ALL throughout the ALL chemotherapy. These were compared with the levels of 16 control subjects and of patient groups with severe neurological diseases. Results During induction, the children with ALL had subnormal CSF IGF-1 levels which improved after 2 months. In seven individuals, two with severe vincristine polyneuropathy, the subnormal levels persisted throughout the chemotherapy. Conclusions Our findings suggest impairment of the IGF-1 trophic system during induction by a mechanism so far unknown. Correlation with disturbed neuronal function could not be statistically proven. © 2004 Wiley-Liss, Inc." @default.
- W2050803707 created "2016-06-24" @default.
- W2050803707 creator A5024091624 @default.
- W2050803707 creator A5030043767 @default.
- W2050803707 creator A5045741099 @default.
- W2050803707 creator A5061345880 @default.
- W2050803707 creator A5082007290 @default.
- W2050803707 date "2004-01-01" @default.
- W2050803707 modified "2023-09-26" @default.
- W2050803707 title "Cerebrospinal fluid insulin-like growth factor (IGF-1) and insulin-like growth factor binding protein (IGFBP-2) in children with acute lymphoblastic leukemia" @default.
- W2050803707 cites W1987081057 @default.
- W2050803707 cites W1990126994 @default.
- W2050803707 cites W2002489309 @default.
- W2050803707 cites W2003329706 @default.
- W2050803707 cites W2018202764 @default.
- W2050803707 cites W2019600891 @default.
- W2050803707 cites W2027260046 @default.
- W2050803707 cites W2033403055 @default.
- W2050803707 cites W2037908014 @default.
- W2050803707 cites W2057696889 @default.
- W2050803707 cites W2069338092 @default.
- W2050803707 cites W2069469650 @default.
- W2050803707 cites W2069527051 @default.
- W2050803707 cites W2070695441 @default.
- W2050803707 cites W2081560586 @default.
- W2050803707 cites W2084580557 @default.
- W2050803707 cites W2085006816 @default.
- W2050803707 cites W2102527735 @default.
- W2050803707 cites W2118457944 @default.
- W2050803707 cites W2118742245 @default.
- W2050803707 cites W2144586195 @default.
- W2050803707 cites W2160211696 @default.
- W2050803707 cites W2400297448 @default.
- W2050803707 cites W2976216518 @default.
- W2050803707 cites W52395525 @default.
- W2050803707 doi "https://doi.org/10.1002/pbc.20072" @default.
- W2050803707 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15236275" @default.
- W2050803707 hasPublicationYear "2004" @default.
- W2050803707 type Work @default.
- W2050803707 sameAs 2050803707 @default.
- W2050803707 citedByCount "8" @default.
- W2050803707 countsByYear W20508037072012 @default.
- W2050803707 countsByYear W20508037072022 @default.
- W2050803707 crossrefType "journal-article" @default.
- W2050803707 hasAuthorship W2050803707A5024091624 @default.
- W2050803707 hasAuthorship W2050803707A5030043767 @default.
- W2050803707 hasAuthorship W2050803707A5045741099 @default.
- W2050803707 hasAuthorship W2050803707A5061345880 @default.
- W2050803707 hasAuthorship W2050803707A5082007290 @default.
- W2050803707 hasConcept C126322002 @default.
- W2050803707 hasConcept C134018914 @default.
- W2050803707 hasConcept C170493617 @default.
- W2050803707 hasConcept C176685330 @default.
- W2050803707 hasConcept C2775892965 @default.
- W2050803707 hasConcept C2775960820 @default.
- W2050803707 hasConcept C2776694085 @default.
- W2050803707 hasConcept C2776755627 @default.
- W2050803707 hasConcept C2779306644 @default.
- W2050803707 hasConcept C2779429289 @default.
- W2050803707 hasConcept C2779651940 @default.
- W2050803707 hasConcept C2780378035 @default.
- W2050803707 hasConcept C2780689927 @default.
- W2050803707 hasConcept C71924100 @default.
- W2050803707 hasConceptScore W2050803707C126322002 @default.
- W2050803707 hasConceptScore W2050803707C134018914 @default.
- W2050803707 hasConceptScore W2050803707C170493617 @default.
- W2050803707 hasConceptScore W2050803707C176685330 @default.
- W2050803707 hasConceptScore W2050803707C2775892965 @default.
- W2050803707 hasConceptScore W2050803707C2775960820 @default.
- W2050803707 hasConceptScore W2050803707C2776694085 @default.
- W2050803707 hasConceptScore W2050803707C2776755627 @default.
- W2050803707 hasConceptScore W2050803707C2779306644 @default.
- W2050803707 hasConceptScore W2050803707C2779429289 @default.
- W2050803707 hasConceptScore W2050803707C2779651940 @default.
- W2050803707 hasConceptScore W2050803707C2780378035 @default.
- W2050803707 hasConceptScore W2050803707C2780689927 @default.
- W2050803707 hasConceptScore W2050803707C71924100 @default.
- W2050803707 hasIssue "2" @default.
- W2050803707 hasLocation W20508037071 @default.
- W2050803707 hasLocation W20508037072 @default.
- W2050803707 hasOpenAccess W2050803707 @default.
- W2050803707 hasPrimaryLocation W20508037071 @default.
- W2050803707 hasRelatedWork W2032111989 @default.
- W2050803707 hasRelatedWork W2053449558 @default.
- W2050803707 hasRelatedWork W2060694919 @default.
- W2050803707 hasRelatedWork W2078978316 @default.
- W2050803707 hasRelatedWork W2087090518 @default.
- W2050803707 hasRelatedWork W2098742882 @default.
- W2050803707 hasRelatedWork W2143316076 @default.
- W2050803707 hasRelatedWork W3080634917 @default.
- W2050803707 hasRelatedWork W4236502113 @default.
- W2050803707 hasRelatedWork W4255621366 @default.
- W2050803707 hasVolume "43" @default.
- W2050803707 isParatext "false" @default.
- W2050803707 isRetracted "false" @default.
- W2050803707 magId "2050803707" @default.
- W2050803707 workType "article" @default.