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- W2050859776 abstract "An intraperitoneal injection of either leucine (1.57 mg/g body wt) or valine (2 mg/g body wt) into newborn mice led to a rapid accumulation of inactive monoribosomes in their brains. Invitro measurements of protein synthesis by the remaining active ribosomes in leucine-treated mice revealed that polypeptide chain elongation was also inhibited. When a mixture of the seven amino acids from the leucine transport system was injected (0.15 mg each amino acid/g body wt) following the valine or leucine treatment, brain monoribosomes did not accumulate and elongation rates in the leucine-treated mice were only slightly altered." @default.
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- W2050859776 title "The inhibition of brain protein synthesis following leucine or valine injection can be prevented" @default.
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- W2050859776 doi "https://doi.org/10.1016/0006-291x(81)90251-5" @default.
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