Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050865517> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2050865517 endingPage "372" @default.
- W2050865517 startingPage "369" @default.
- W2050865517 abstract "This study was designed to investigate the time course of acute cutaneous photosensitivity following administration of Photofrin II using the murine ear swelling response (ESR) as an in vivo end-point. Ros:(ICR) mice were injected with 5 mg/kg Photofrin II and illuminated 7.5 h to 31 days later with 630-nm laser light; ESR was measured 24 h after illumination. There was a direct correlation between ESR and the concentration of [14C]Photofrin II in blood, while no relationship between ESR and the level of [14C]Photofrin II in the ear tissue of exsanguinated mice was evident. Photosensitivity in the mouse foot can be suppressed by preexposure to low doses of light via a photochemical destruction of tissue-bound sensitizer (Boyle and Potter, 1987, Photochem. Photobiol. 46, 997-1001). However, mouse ears pretreated with 84 J/cm2 of 630-nm light (28 J/cm2/day, given 2, 4 and 6 d after injection), a dose sufficient to reduce porphyrin fluorescence in ear tissue by about 75%, prior to the usual light dose (88.6 J/cm2, 630 nm, day 9 after injection) showed a mean ESR not significantly different (P less than 0.5) from that for ears which received only a single dose of 88.6 J/cm2 on day 9. It is concluded, for this animal model, that circulating porphyrin is the source of photoinduced ear-tissue edema and that photobleaching of tissue-bound sensitizer does not attenuate ear-tissue photosensitivity." @default.
- W2050865517 created "2016-06-24" @default.
- W2050865517 creator A5010197450 @default.
- W2050865517 creator A5065629135 @default.
- W2050865517 date "1989-03-01" @default.
- W2050865517 modified "2023-09-27" @default.
- W2050865517 title "THE TIME COURSE OF CUTANEOUS PORPHYRIN PHOTOSENSITIZATION IN THE MURINE EAR" @default.
- W2050865517 cites W1975244761 @default.
- W2050865517 cites W1983956363 @default.
- W2050865517 cites W1993680977 @default.
- W2050865517 cites W2052031545 @default.
- W2050865517 cites W2052327108 @default.
- W2050865517 cites W2074771377 @default.
- W2050865517 cites W2087404609 @default.
- W2050865517 cites W2092365181 @default.
- W2050865517 cites W2094890044 @default.
- W2050865517 cites W2122327980 @default.
- W2050865517 cites W2127298293 @default.
- W2050865517 cites W2145715284 @default.
- W2050865517 doi "https://doi.org/10.1111/j.1751-1097.1989.tb04121.x" @default.
- W2050865517 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2525262" @default.
- W2050865517 hasPublicationYear "1989" @default.
- W2050865517 type Work @default.
- W2050865517 sameAs 2050865517 @default.
- W2050865517 citedByCount "34" @default.
- W2050865517 countsByYear W20508655172019 @default.
- W2050865517 crossrefType "journal-article" @default.
- W2050865517 hasAuthorship W2050865517A5010197450 @default.
- W2050865517 hasAuthorship W2050865517A5065629135 @default.
- W2050865517 hasConcept C120665830 @default.
- W2050865517 hasConcept C121332964 @default.
- W2050865517 hasConcept C12554922 @default.
- W2050865517 hasConcept C126322002 @default.
- W2050865517 hasConcept C141071460 @default.
- W2050865517 hasConcept C150903083 @default.
- W2050865517 hasConcept C185592680 @default.
- W2050865517 hasConcept C186807665 @default.
- W2050865517 hasConcept C192562407 @default.
- W2050865517 hasConcept C207001950 @default.
- W2050865517 hasConcept C2779121184 @default.
- W2050865517 hasConcept C2779480358 @default.
- W2050865517 hasConcept C2780886150 @default.
- W2050865517 hasConcept C31332276 @default.
- W2050865517 hasConcept C49040817 @default.
- W2050865517 hasConcept C71924100 @default.
- W2050865517 hasConcept C75473681 @default.
- W2050865517 hasConcept C86803240 @default.
- W2050865517 hasConcept C91881484 @default.
- W2050865517 hasConceptScore W2050865517C120665830 @default.
- W2050865517 hasConceptScore W2050865517C121332964 @default.
- W2050865517 hasConceptScore W2050865517C12554922 @default.
- W2050865517 hasConceptScore W2050865517C126322002 @default.
- W2050865517 hasConceptScore W2050865517C141071460 @default.
- W2050865517 hasConceptScore W2050865517C150903083 @default.
- W2050865517 hasConceptScore W2050865517C185592680 @default.
- W2050865517 hasConceptScore W2050865517C186807665 @default.
- W2050865517 hasConceptScore W2050865517C192562407 @default.
- W2050865517 hasConceptScore W2050865517C207001950 @default.
- W2050865517 hasConceptScore W2050865517C2779121184 @default.
- W2050865517 hasConceptScore W2050865517C2779480358 @default.
- W2050865517 hasConceptScore W2050865517C2780886150 @default.
- W2050865517 hasConceptScore W2050865517C31332276 @default.
- W2050865517 hasConceptScore W2050865517C49040817 @default.
- W2050865517 hasConceptScore W2050865517C71924100 @default.
- W2050865517 hasConceptScore W2050865517C75473681 @default.
- W2050865517 hasConceptScore W2050865517C86803240 @default.
- W2050865517 hasConceptScore W2050865517C91881484 @default.
- W2050865517 hasIssue "3" @default.
- W2050865517 hasLocation W20508655171 @default.
- W2050865517 hasLocation W20508655172 @default.
- W2050865517 hasOpenAccess W2050865517 @default.
- W2050865517 hasPrimaryLocation W20508655171 @default.
- W2050865517 hasRelatedWork W1965267150 @default.
- W2050865517 hasRelatedWork W1979569657 @default.
- W2050865517 hasRelatedWork W1986673804 @default.
- W2050865517 hasRelatedWork W2005552449 @default.
- W2050865517 hasRelatedWork W2052940040 @default.
- W2050865517 hasRelatedWork W2127298293 @default.
- W2050865517 hasRelatedWork W2198850752 @default.
- W2050865517 hasRelatedWork W2315602870 @default.
- W2050865517 hasRelatedWork W3049684266 @default.
- W2050865517 hasRelatedWork W3121512756 @default.
- W2050865517 hasVolume "49" @default.
- W2050865517 isParatext "false" @default.
- W2050865517 isRetracted "false" @default.
- W2050865517 magId "2050865517" @default.
- W2050865517 workType "article" @default.