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- W2050876043 abstract "Treatment of latent tuberculosis (TB) infection is an important component of TB control programs in both high- and low-prevalence countries. Clinical trials of treatment of latent TB conducted over several decades have demonstrated that preventive treatment can reduce the risk of developing active TB up to 90%. Although 9 months of daily, self-administered isoniazid has been the most widely used and recommended regimen for the treatment of latent infection, other regimens such as 3 months of daily isoniazid and rifampin, or 4 months of daily rifampin alone have also been recommended and used. Most recently, a 12-dose regimen of once-weekly isoniazid and rifapentine has been shown to be noninferior to 9 months of daily isoniazid in a large and well conducted clinical trial. Adoption of such a regimen on a large scale could have significant implications for TB elimination efforts." @default.
- W2050876043 created "2016-06-24" @default.
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- W2050876043 date "2013-09-20" @default.
- W2050876043 modified "2023-10-04" @default.
- W2050876043 title "Treatment of latent tuberculosis infection" @default.
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- W2050876043 doi "https://doi.org/10.1177/1753465813503028" @default.
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