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- W2050877576 abstract "Disintegrins are short soluble integrin ligands that were initially identified in snake venom. A previously recognized cellular protein with a disintegrin domain was the guinea pig sperm protein PH-30, a protein implicated in sperm-egg membrane binding and fusion. Here we present peptide sequences that are characteristic for several cellular disintegrin-domain proteins. These peptide sequences were deduced from cDNA sequence tags that were generated by polymerase chain reaction from various mouse tissue and a mouse muscle cell line. Northern blot analysis with four sequence tags revealed distinct mRNA expression patterns. Evidently, cellular proteins containing a disintegrin domain define a superfamily of potential integrin ligands that are likely to function in important cell-cell and cell-matrix interactions." @default.
- W2050877576 created "2016-06-24" @default.
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- W2050877576 date "1994-03-29" @default.
- W2050877576 modified "2023-09-23" @default.
- W2050877576 title "A family of cellular proteins related to snake venom disintegrins." @default.
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- W2050877576 doi "https://doi.org/10.1073/pnas.91.7.2748" @default.
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