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- W2050881036 abstract "ABSTRACT A quartz crystal microbalance (QCM) biosensor was developed for the detection of endotoxin (lipopolysaccharide, LPS). Polymyxin B (PMB), which binds to endotoxins of gram-negative bacteria, was immobilized on the self-assembled monolayer (SAM) modified 10 MHz AT-cut quartz crystal resonator. The SAM's were activated with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) prior to PMB immobilization. The resulting frequency change due to the adsorption of endotoxin was measured. The linear correlation could be obtained from 2.5 to 20 pg/mL. Keywords: Quartz crystalBiosensorEndotoxinSelf-assembled monolayer Acknowledgments" @default.
- W2050881036 created "2016-06-24" @default.
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- W2050881036 date "2002-09-17" @default.
- W2050881036 modified "2023-09-23" @default.
- W2050881036 title "SELF-ASSEMBLED MONOLAYER BASED QUARTZ CRYSTAL BIOSENSORS FOR THE DETECTION OF ENDOTOXINS" @default.
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- W2050881036 doi "https://doi.org/10.1081/al-120013582" @default.
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