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- W2050893642 abstract "From the latex of Synadenium grantii Hook F. (Euphorbiaceae) were isolated by chromatographic methods five diterpene 12,13-diesters of the tigliane-type parent alcohols 4-deoxyphorbol (1a), 4,20-dideoxy-5α-hydroxyphorbol (2a) and 20-deoxy-5α-hydroxyphorbol (3a) with isobutyric, tiglic and phenylacetic acid. Of these, 4-deoxyphorbol-13-(phenylacetate)-12-tiglate (1f) turned out to be highly irritant on the mouse ear while the rest of the esters had rather low or no irritant activity; 1f was also assayed for tumor-promoting activity and proved to be almost inactive." @default.
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- W2050893642 date "1988-12-01" @default.
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- W2050893642 title "Tigliane-Type Diterpene Esters from<i>Synadenium grantii</i><sup>1,5</sup>" @default.
- W2050893642 doi "https://doi.org/10.1055/s-2006-962531" @default.
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