FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050910147> ?p ?o ?g. }

• W2050910147 endingPage "38" @default.
• W2050910147 startingPage "31" @default.
• W2050910147 abstract "Tetrabromobisphenol-A (TBBPA) is currently the most widely used brominated flame retardant (BFR) and has been proven to have a very high toxicity to aquatic organisms including bivalves. However, molecular responses to TBBPA in bivalve remain largely unknown. Novel high-throughput deep sequencing technology has been a powerful tool for looking at molecular responses to toxicological stressors in organisms. Using Illumina's digital gene expression (DGE) system, we investigated TBBPA-induced transcriptome response in the digestive gland tissue of scallop Chlamys farreri. In total, 173 and 266 genes were identified as significantly up- or down-regulated, respectively. Functional analysis based on gene ontology (GO) classification system and Kyoto Encyclopedia of Genes and Genomes (KEGG) database revealed that TBBPA significantly altered the expression of genes involved in stress response, detoxification, antioxidation, and innate immunity which were extensively discussed. In particular, evidence for the endocrine disrupting effect of TBBPA on bivalve was first obtained in this study. Quantitative real-time PCR was performed to ascertain the mRNA expression of several genes identified by the DGE analysis. The results of this study may serve as a basis for future research on molecular mechanism of toxic effects of TBBPA on marine bivalves." @default.
• W2050910147 created "2016-06-24" @default.
• W2050910147 creator A5012182461 @default.
• W2050910147 creator A5032909560 @default.
• W2050910147 creator A5040589149 @default.
• W2050910147 creator A5040739347 @default.
• W2050910147 creator A5046775442 @default.
• W2050910147 date "2015-02-01" @default.
• W2050910147 modified "2023-09-24" @default.
• W2050910147 title "Deep sequencing of the scallop Chlamys farreri transcriptome response to tetrabromobisphenol A (TBBPA) stress" @default.
• W2050910147 cites W1925686649 @default.
• W2050910147 cites W1964778811 @default.
• W2050910147 cites W1964880546 @default.
• W2050910147 cites W1965809297 @default.
• W2050910147 cites W1970227553 @default.
• W2050910147 cites W1970449952 @default.
• W2050910147 cites W1970658145 @default.
• W2050910147 cites W1971268168 @default.
• W2050910147 cites W1971899779 @default.
• W2050910147 cites W1974204093 @default.
• W2050910147 cites W1975700888 @default.
• W2050910147 cites W1977610850 @default.
• W2050910147 cites W1981509058 @default.
• W2050910147 cites W1982870743 @default.
• W2050910147 cites W1983497821 @default.
• W2050910147 cites W1985599173 @default.
• W2050910147 cites W1985657119 @default.
• W2050910147 cites W1986593268 @default.
• W2050910147 cites W1987935045 @default.
• W2050910147 cites W1989125351 @default.
• W2050910147 cites W1989583775 @default.
• W2050910147 cites W1990305972 @default.
• W2050910147 cites W1995844276 @default.
• W2050910147 cites W1997208147 @default.
• W2050910147 cites W1999574084 @default.
• W2050910147 cites W2001315330 @default.
• W2050910147 cites W2003770920 @default.
• W2050910147 cites W2005452204 @default.
• W2050910147 cites W2005774650 @default.
• W2050910147 cites W2006397803 @default.
• W2050910147 cites W2011508520 @default.
• W2050910147 cites W2011802749 @default.
• W2050910147 cites W2013024553 @default.
• W2050910147 cites W2017300013 @default.
• W2050910147 cites W2020505886 @default.
• W2050910147 cites W2029485994 @default.
• W2050910147 cites W2029867542 @default.
• W2050910147 cites W2035909576 @default.
• W2050910147 cites W2036274594 @default.
• W2050910147 cites W2042165012 @default.
• W2050910147 cites W2045627369 @default.
• W2050910147 cites W2046729564 @default.
• W2050910147 cites W2047121384 @default.
• W2050910147 cites W2052884565 @default.
• W2050910147 cites W2053289664 @default.
• W2050910147 cites W2053417122 @default.
• W2050910147 cites W2062257143 @default.
• W2050910147 cites W2062546148 @default.
• W2050910147 cites W2065469488 @default.
• W2050910147 cites W2066807568 @default.
• W2050910147 cites W2072367432 @default.
• W2050910147 cites W2076979866 @default.
• W2050910147 cites W2078861858 @default.
• W2050910147 cites W2081085539 @default.
• W2050910147 cites W2083135851 @default.
• W2050910147 cites W2090333455 @default.
• W2050910147 cites W2090834142 @default.
• W2050910147 cites W2091819856 @default.
• W2050910147 cites W2092865865 @default.
• W2050910147 cites W2093029210 @default.
• W2050910147 cites W2094347731 @default.
• W2050910147 cites W2095470365 @default.
• W2050910147 cites W2100492886 @default.
• W2050910147 cites W2103275378 @default.
• W2050910147 cites W2104802986 @default.
• W2050910147 cites W2104840560 @default.
• W2050910147 cites W2107060225 @default.
• W2050910147 cites W2108244474 @default.
• W2050910147 cites W2114219560 @default.
• W2050910147 cites W2118058166 @default.
• W2050910147 cites W2119013116 @default.
• W2050910147 cites W2119034410 @default.
• W2050910147 cites W2126387583 @default.
• W2050910147 cites W2126419817 @default.
• W2050910147 cites W2132024398 @default.
• W2050910147 cites W2133449490 @default.
• W2050910147 cites W2158297569 @default.
• W2050910147 cites W2164154943 @default.
• W2050910147 cites W2318467540 @default.
• W2050910147 doi "https://doi.org/10.1016/j.margen.2014.09.004" @default.
• W2050910147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25260812" @default.
• W2050910147 hasPublicationYear "2015" @default.
• W2050910147 type Work @default.
• W2050910147 sameAs 2050910147 @default.
• W2050910147 citedByCount "26" @default.
• W2050910147 countsByYear W20509101472015 @default.
• W2050910147 countsByYear W20509101472016 @default.
• W2050910147 countsByYear W20509101472017 @default.

• next