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• W2050969673 abstract "Aplastic anemia is a rare, potentially lethal disease that occurs when the bone marrow stops making enough blood cells. The condition results in complete bone marrow failure and aplasia. Common life threatening complications include infection, bleeding, and anemia. The cause of aplastic anemia is unknown but may be linked to injury to the bone marrow from radiation, chemicals, viruses, and other causes. The initial diagnosis of aplastic anemia is often a medical emergency requiring hospitalization and isolation. The diagnosis is typically made via peripheral blood sampling and a bone marrow aspirate. Supportive care during the initial period typically consists of blood component replacement and antimicrobial coverage to reduce and treat life-threatening infections. The gold standard of cure for these patients is bone marrow or stem cell transplantation. The Duke Pediatric Stem Cell Transplant Program has performed 22 transplantations on children with aplastic anemia. The aims ofthis abstract are as follows: 1To define and describe the potential causes of aplastic anemia.2To describe the symptoms associated with the onset of the disease, as well as the sequelae seen with the progression of this disease.3To review the latest treatment options, including a detailed analysis of bone marrow and stem cell transplantation in this patient population.4To provide a detailed description of the Duke Pediatric Stem Cell Transplantation experience regarding this patient population.5To provide statistics on the outcomes of transplantation in this group of children.6To identify nursing strategies for the care and support of these patients. Aplastic anemia is a rare, potentially lethal disease that occurs when the bone marrow stops making enough blood cells. The condition results in complete bone marrow failure and aplasia. Common life threatening complications include infection, bleeding, and anemia. The cause of aplastic anemia is unknown but may be linked to injury to the bone marrow from radiation, chemicals, viruses, and other causes. The initial diagnosis of aplastic anemia is often a medical emergency requiring hospitalization and isolation. The diagnosis is typically made via peripheral blood sampling and a bone marrow aspirate. Supportive care during the initial period typically consists of blood component replacement and antimicrobial coverage to reduce and treat life-threatening infections. The gold standard of cure for these patients is bone marrow or stem cell transplantation. The Duke Pediatric Stem Cell Transplant Program has performed 22 transplantations on children with aplastic anemia. The aims ofthis abstract are as follows: 1To define and describe the potential causes of aplastic anemia.2To describe the symptoms associated with the onset of the disease, as well as the sequelae seen with the progression of this disease.3To review the latest treatment options, including a detailed analysis of bone marrow and stem cell transplantation in this patient population.4To provide a detailed description of the Duke Pediatric Stem Cell Transplantation experience regarding this patient population.5To provide statistics on the outcomes of transplantation in this group of children.6To identify nursing strategies for the care and support of these patients." @default.
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• W2050969673 date "2005-02-01" @default.
• W2050969673 modified "2023-09-26" @default.
• W2050969673 title "Treatment options and nursing care for the pediatric aplastic anemia patient requriring bone marrow or stem cell transplantation" @default.
• W2050969673 doi "https://doi.org/10.1016/j.bbmt.2004.12.291" @default.
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