Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051041806> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2051041806 endingPage "627" @default.
- W2051041806 startingPage "627" @default.
- W2051041806 abstract "TO THE EDITOR: We appreciate the comments by Ercin et al. ((1)) regarding our recent article reporting a strong, graded, association between the histological severity of nonalcoholic steatohepatitis (NASH) and plasma inflammatory/procoagulant biomarkers in adult men ((2)). As stated in the article, we included all of the 45 consecutive patients with NASH, who had been previously included in another published study ((3)). More details on study design, methods, and baseline characteristics of NASH participants have been published in that study. Overall, in our article ((2)), we included six type 2 diabetic patients among participants with NASH and five diabetic patients among those with overweight alone. None of them was taking hypoglycemic medications or other medications known to affect plasma adiponectin and inflammatory biomarkers. Only one participant with NASH had impaired glucose tolerance. Oral glucose tolerance test was not extensively performed in overweight nonsteatotic participants. Thus, the number of participants with type 2 diabetes was essentially the same between the two groups, but it was too small to perform separate analyses by diabetes status. Notably, the results presented in Table 1 of our article ((2)) remained unchanged after excluding all participants with type 2 diabetes. In particular, NASH patients had a greater insulin resistance and higher values of plasma triglycerides, high-sensitivity C-reactive protein (hs-CRP), plasminogen activator inhibitor-1 (PAI-1) activity and fibrinogen concentrations, and lower plasma adiponectin levels than overweight nonsteatotic patients despite similar values of BMI and visceral adiposity. Similarly, the results presented in Figure 1 remained the same when NASH patients with type 2 diabetes or impaired glucose tolerance (n = 7) were excluded from analysis. Also in this case, the severity of liver histology in NASH patients (n = 38) was strongly associated (P < 0.01 or less for all trends) with increasing plasma hs-CRP, PAI-1 activity and fibrinogen concentrations, and decreasing plasma adiponectin concentrations. The authors declared no conflict of interest." @default.
- W2051041806 created "2016-06-24" @default.
- W2051041806 creator A5071075382 @default.
- W2051041806 creator A5073522064 @default.
- W2051041806 creator A5084307747 @default.
- W2051041806 date "2009-04-01" @default.
- W2051041806 modified "2023-09-24" @default.
- W2051041806 title "Response to “NASH Predicts Plasma Inflammatory Biomarkers Independently of Visceral Fat in Men”" @default.
- W2051041806 cites W2034674595 @default.
- W2051041806 cites W2069553469 @default.
- W2051041806 doi "https://doi.org/10.1038/oby.2008.611" @default.
- W2051041806 hasPublicationYear "2009" @default.
- W2051041806 type Work @default.
- W2051041806 sameAs 2051041806 @default.
- W2051041806 citedByCount "0" @default.
- W2051041806 crossrefType "journal-article" @default.
- W2051041806 hasAuthorship W2051041806A5071075382 @default.
- W2051041806 hasAuthorship W2051041806A5073522064 @default.
- W2051041806 hasAuthorship W2051041806A5084307747 @default.
- W2051041806 hasBestOaLocation W20510418061 @default.
- W2051041806 hasConcept C126322002 @default.
- W2051041806 hasConcept C134018914 @default.
- W2051041806 hasConcept C2776782570 @default.
- W2051041806 hasConcept C2776954865 @default.
- W2051041806 hasConcept C2777180221 @default.
- W2051041806 hasConcept C2777391703 @default.
- W2051041806 hasConcept C2778772119 @default.
- W2051041806 hasConcept C2779134260 @default.
- W2051041806 hasConcept C2780586474 @default.
- W2051041806 hasConcept C3018708256 @default.
- W2051041806 hasConcept C511355011 @default.
- W2051041806 hasConcept C555293320 @default.
- W2051041806 hasConcept C71924100 @default.
- W2051041806 hasConcept C77350462 @default.
- W2051041806 hasConcept C90924648 @default.
- W2051041806 hasConceptScore W2051041806C126322002 @default.
- W2051041806 hasConceptScore W2051041806C134018914 @default.
- W2051041806 hasConceptScore W2051041806C2776782570 @default.
- W2051041806 hasConceptScore W2051041806C2776954865 @default.
- W2051041806 hasConceptScore W2051041806C2777180221 @default.
- W2051041806 hasConceptScore W2051041806C2777391703 @default.
- W2051041806 hasConceptScore W2051041806C2778772119 @default.
- W2051041806 hasConceptScore W2051041806C2779134260 @default.
- W2051041806 hasConceptScore W2051041806C2780586474 @default.
- W2051041806 hasConceptScore W2051041806C3018708256 @default.
- W2051041806 hasConceptScore W2051041806C511355011 @default.
- W2051041806 hasConceptScore W2051041806C555293320 @default.
- W2051041806 hasConceptScore W2051041806C71924100 @default.
- W2051041806 hasConceptScore W2051041806C77350462 @default.
- W2051041806 hasConceptScore W2051041806C90924648 @default.
- W2051041806 hasIssue "4" @default.
- W2051041806 hasLocation W20510418061 @default.
- W2051041806 hasOpenAccess W2051041806 @default.
- W2051041806 hasPrimaryLocation W20510418061 @default.
- W2051041806 hasRelatedWork W1982589044 @default.
- W2051041806 hasRelatedWork W1988439151 @default.
- W2051041806 hasRelatedWork W2000536767 @default.
- W2051041806 hasRelatedWork W2035107691 @default.
- W2051041806 hasRelatedWork W2066062695 @default.
- W2051041806 hasRelatedWork W2120688902 @default.
- W2051041806 hasRelatedWork W2124038922 @default.
- W2051041806 hasRelatedWork W2136767406 @default.
- W2051041806 hasRelatedWork W2375944679 @default.
- W2051041806 hasRelatedWork W3028839963 @default.
- W2051041806 hasVolume "17" @default.
- W2051041806 isParatext "false" @default.
- W2051041806 isRetracted "false" @default.
- W2051041806 magId "2051041806" @default.
- W2051041806 workType "article" @default.