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• W2051052655 abstract "It is widely accepted that the large trinucleotide repeat expansions observed in many neurological diseases occur during replication. However, genetic recombination has emerged as a major source of instability for tandem repeats, including minisatellites, and recent studies raise the possibility that it may also be responsible for trinucleotide repeat expansions. We will review data connecting tandem repeat rearrangements and recombination in humans and in eukaryotic model organisms, and discuss the possible role of recombination in trinucleotide repeat expansions in human neurological disorders." @default.
• W2051052655 created "2016-06-24" @default.
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• W2051052655 date "2000-08-01" @default.
• W2051052655 modified "2023-10-12" @default.
• W2051052655 title "Mini‐ and microsatellite expansions: the recombination connection" @default.
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• W2051052655 doi "https://doi.org/10.1093/embo-reports/kvd031" @default.
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