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- W2051101220 abstract "The aim of this study was to investigate the regional importance of gamma delta T cells in cutaneous lesions of Langerhans' cell histiocytosis. Six cases of Langerhans' cell histiocytosis were investigated by immunohistochemical techniques (alkaline phosphatase-antialkaline phosphatase complex and indirect immunoperoxidase). Increase of gamma delta T cells was observed in 3 cases of Langerhans' cell histiocytosis. In these cases up to 30% of CD3+ cells stained with an anti-TCR gamma delta monoclonal antibodies and in two of them gamma delta T cells showed a marked epidermotropism. In the specimens of the remaining three cases gamma delta T cells were found in an overall percentage of 5% of CD3+ cells, but in two cases a significant increase of epidermal gamma delta T cells was observed. The finding of numerous gamma delta T cells in Langerhans' cell histiocytosis is provocative and supports the suggestion of a functional relationship between gamma delta T cells and LCH cells." @default.
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- W2051101220 date "1993-01-01" @default.
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- W2051101220 title "T-Lymphocytes bearing the γδ T-cell receptor in cutaneous lesions of langerhans' cell histiocytosis" @default.
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- W2051101220 doi "https://doi.org/10.1002/mpo.2950210507" @default.
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