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• W2051102557 abstract "The soluble domains of the envelope glycoprotein of HIV-1 (gp120) and human CD4 (sCD4) have been individually expressed in insect cells using recombinant baculoviruses. Each product is secreted from infected cells and accumulates in the surrounding media to levels of 1-2 mg/liter of 2 × 109 cells. Both molecules have full biological activity, and conditioned media from infected cells have been used to establish a simple assay for gp120-sCD4 interaction that is highly specific and amenable to mass screening. The crystallization of sCD4 purified from this source is reported." @default.
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• W2051102557 date "1990-06-01" @default.
• W2051102557 modified "2023-10-05" @default.
• W2051102557 title "Expression of HIV-1 gp120 and Human Soluble CD4 by Recombinant Baculoviruses and their Interaction In Vitro" @default.
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• W2051102557 doi "https://doi.org/10.1089/aid.1990.6.765" @default.
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