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- W2051103410 abstract "A technique of serum lipoprotein analysis by polyacrylamide gel disc electrophoresis has been developed and compared to the agarose gel technique. More than 400 samples were obtained from 135 persons with normal and abnormal serum lipids. Pre-β-lipoproteins (VLDL) migrate only a short distance in a 3.25% polyacrylamide gel and are widely separated from the β-lipoprotein fraction (LDL). Disc electrophoresis in polyacrylamide gel is a rather sensitive method, however slightly more difficult and fraught with potential problems. The clinical use of the disc electrophoresis method is limited. Results obtained by both methods in patients with hyperlipoproteinemias and patients with liver disaese are comparable, differences are pointed out. Es wird eine Technik der Disk-Elektrophorese menschlicher Serumlipoproteine beschrieben und mit der Elektrophorese in Agarose-Gel verglichen. Über 400 Serumproben von 135 Personen mit normalen und pathologischen Lipidwerten wurden untersucht. Prä-β-Lipoproteine (VLDL) wandern in der Disk-Elektrophorese nur wenig und erscheinen weit getrennt von der Bande der β-Lipoproteine (LDL). Die Disk-Elektrophorese in PAA-Gel ist empfindlicher, methodisch jedoch schwieriger und störanfälliger als die Elektrophorese in Agarose-Gel. Ihre Anwendung für Routineuntersuchungen erscheint nicht angezeigt. Die Befunde bei Hyperlipoproteinämien und Lebererkrankungen sind vergleichbar, auf Unterschiede wird hingewiesen." @default.
- W2051103410 created "2016-06-24" @default.
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- W2051103410 date "1970-09-01" @default.
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- W2051103410 title "Vergleichende untersuchungen der lipoproteine des serums mit der agarosegel-elektrophorese und der disk-elektrophorese in polyacrylamid-gel" @default.
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- W2051103410 doi "https://doi.org/10.1016/0009-8981(70)90011-2" @default.
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