FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051132500> ?p ?o ?g. }

• W2051132500 endingPage "241" @default.
• W2051132500 startingPage "231" @default.
• W2051132500 abstract "Retinal ganglion cells (RGCs) death caused by oxidative stress is a common risk factor for glaucoma. In the present study, 8-hydroxycalamenene was isolated from the hexane fraction of Reynoutria elliptica. We showed that 8-hydroxycalamenene attenuated the cell death of transformed RGC-5 cells. This compound also produced a dose-dependent decrease in the expression of apoptotic proteins (cleaved PARP and caspase-3) induced by l-buthionine-(S,R)-sulfoximine (BSO) plus glutamate and stimulated glutathione and glutathione S-transferase activity. Moreover, the addition of 8-hydroxycalamenene to cell cultures restored the reduced mitochondrial membrane potential resulting from glutamate/BSO treatment. The presence of N-methyl-d-aspartate in the retina of rats affected the thickness of the inner plexiform layer (IPL) and increased the number of TUNEL-positive RGCs. However, 8-hydroxycalamenene protected against thinning of the IPL and reduced TUNEL-positive cells in the ganglion cell layer. Thus, 8-hydroxycalamenene isolated from R. elliptica exerts neuroprotective effects both in vitro and in vivo." @default.
• W2051132500 created "2016-06-24" @default.
• W2051132500 creator A5001686682 @default.
• W2051132500 creator A5007034431 @default.
• W2051132500 creator A5010141317 @default.
• W2051132500 creator A5032275860 @default.
• W2051132500 creator A5048542413 @default.
• W2051132500 date "2013-01-01" @default.
• W2051132500 modified "2023-09-25" @default.
• W2051132500 title "8-Hydroxycalamenene isolated from the rhizomes of Reynoutria elliptica exerts neuroprotective effects both in vitro and in vivo" @default.
• W2051132500 cites W1514719303 @default.
• W2051132500 cites W1588826234 @default.
• W2051132500 cites W1604048158 @default.
• W2051132500 cites W1910727610 @default.
• W2051132500 cites W1964220992 @default.
• W2051132500 cites W1965780404 @default.
• W2051132500 cites W1976061556 @default.
• W2051132500 cites W1996833863 @default.
• W2051132500 cites W2026793735 @default.
• W2051132500 cites W2057473822 @default.
• W2051132500 cites W2061766512 @default.
• W2051132500 cites W2062171726 @default.
• W2051132500 cites W2063221399 @default.
• W2051132500 cites W2067572554 @default.
• W2051132500 cites W2086559976 @default.
• W2051132500 cites W2090302584 @default.
• W2051132500 cites W2092199160 @default.
• W2051132500 cites W2094776609 @default.
• W2051132500 cites W2113805782 @default.
• W2051132500 cites W2114918609 @default.
• W2051132500 cites W2129111836 @default.
• W2051132500 cites W2131375669 @default.
• W2051132500 cites W2135057523 @default.
• W2051132500 cites W2169113983 @default.
• W2051132500 cites W2173351187 @default.
• W2051132500 doi "https://doi.org/10.1016/j.fct.2012.09.025" @default.
• W2051132500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23032515" @default.
• W2051132500 hasPublicationYear "2013" @default.
• W2051132500 type Work @default.
• W2051132500 sameAs 2051132500 @default.
• W2051132500 citedByCount "5" @default.
• W2051132500 countsByYear W20511325002015 @default.
• W2051132500 countsByYear W20511325002017 @default.
• W2051132500 countsByYear W20511325002019 @default.
• W2051132500 countsByYear W20511325002020 @default.
• W2051132500 crossrefType "journal-article" @default.
• W2051132500 hasAuthorship W2051132500A5001686682 @default.
• W2051132500 hasAuthorship W2051132500A5007034431 @default.
• W2051132500 hasAuthorship W2051132500A5010141317 @default.
• W2051132500 hasAuthorship W2051132500A5032275860 @default.
• W2051132500 hasAuthorship W2051132500A5048542413 @default.
• W2051132500 hasConcept C153911025 @default.
• W2051132500 hasConcept C170493617 @default.
• W2051132500 hasConcept C181199279 @default.
• W2051132500 hasConcept C185592680 @default.
• W2051132500 hasConcept C190283241 @default.
• W2051132500 hasConcept C196795494 @default.
• W2051132500 hasConcept C25498285 @default.
• W2051132500 hasConcept C2776151105 @default.
• W2051132500 hasConcept C2777476445 @default.
• W2051132500 hasConcept C2777624874 @default.
• W2051132500 hasConcept C2780188069 @default.
• W2051132500 hasConcept C2780827179 @default.
• W2051132500 hasConcept C31573885 @default.
• W2051132500 hasConcept C538909803 @default.
• W2051132500 hasConcept C55493867 @default.
• W2051132500 hasConcept C61174792 @default.
• W2051132500 hasConcept C86803240 @default.
• W2051132500 hasConcept C95444343 @default.
• W2051132500 hasConcept C98274493 @default.
• W2051132500 hasConceptScore W2051132500C153911025 @default.
• W2051132500 hasConceptScore W2051132500C170493617 @default.
• W2051132500 hasConceptScore W2051132500C181199279 @default.
• W2051132500 hasConceptScore W2051132500C185592680 @default.
• W2051132500 hasConceptScore W2051132500C190283241 @default.
• W2051132500 hasConceptScore W2051132500C196795494 @default.
• W2051132500 hasConceptScore W2051132500C25498285 @default.
• W2051132500 hasConceptScore W2051132500C2776151105 @default.
• W2051132500 hasConceptScore W2051132500C2777476445 @default.
• W2051132500 hasConceptScore W2051132500C2777624874 @default.
• W2051132500 hasConceptScore W2051132500C2780188069 @default.
• W2051132500 hasConceptScore W2051132500C2780827179 @default.
• W2051132500 hasConceptScore W2051132500C31573885 @default.
• W2051132500 hasConceptScore W2051132500C538909803 @default.
• W2051132500 hasConceptScore W2051132500C55493867 @default.
• W2051132500 hasConceptScore W2051132500C61174792 @default.
• W2051132500 hasConceptScore W2051132500C86803240 @default.
• W2051132500 hasConceptScore W2051132500C95444343 @default.
• W2051132500 hasConceptScore W2051132500C98274493 @default.
• W2051132500 hasLocation W20511325001 @default.
• W2051132500 hasLocation W20511325002 @default.
• W2051132500 hasOpenAccess W2051132500 @default.
• W2051132500 hasPrimaryLocation W20511325001 @default.
• W2051132500 hasRelatedWork W108819547 @default.
• W2051132500 hasRelatedWork W122249577 @default.
• W2051132500 hasRelatedWork W1966779294 @default.
• W2051132500 hasRelatedWork W1981931963 @default.
• W2051132500 hasRelatedWork W1994141436 @default.

• next