FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051200345> ?p ?o ?g. }

• W2051200345 endingPage "142" @default.
• W2051200345 startingPage "131" @default.
• W2051200345 abstract "The effect of Prudhoe Bay crude oil (PBCO) and its different fractions [aliphatic, aromatic, heterocyclic (NOS)] on the bioenergetic functions of isolated rat liver mitochondria were studied. A DMSO extract of PBCO inhibited state 3 respiration (in the presence of ADP) with either succinate or β-hydroxybutyrate as substrate. The ascorbate-TMPD dependent state 3 respiration was not affected. Succinate dehydrogenase and β-hydroxybutyrate dehydrogenase activities were also lost in the presence of the PBCO extract suggesting that inhibition of state 3 respiration may be due to blockage of the electron transport chain. Stimulation of state 4 respiration (in the absence of ADP) and of the oligomycin sensitive ATPase activity by the PBCO extract was observed. Fractionation of PBCO indicated that the aromatic fraction was mainly responsible for its inhibitory effects. By comparison, the heterocyclic fraction had weak inhibitory properties while the aliphatic fraction was essentially inactive. It is concluded that the aromatic components of PBCO inhibit mitochondrial respiration and oxidative phosphorylation mainly through impairment of the mitochondrial membrane and inhibition of β-hydroxybutyrate and succinate dehydrogenase supported electron transfer activities of the respiratory chain." @default.
• W2051200345 created "2016-06-24" @default.
• W2051200345 creator A5034578625 @default.
• W2051200345 creator A5054230557 @default.
• W2051200345 creator A5063473062 @default.
• W2051200345 creator A5087210147 @default.
• W2051200345 date "1986-12-15" @default.
• W2051200345 modified "2023-10-16" @default.
• W2051200345 title "Mechanisms of petroleum hydrocarbon toxicity: Studies on the response of rat liver mitochondria to Prudhoe Bay crude oil and its aliphatic, aromatic and heterocyclic fractions" @default.
• W2051200345 cites W119802141 @default.
• W2051200345 cites W131931510 @default.
• W2051200345 cites W144610484 @default.
• W2051200345 cites W1494587255 @default.
• W2051200345 cites W1555316766 @default.
• W2051200345 cites W1562914594 @default.
• W2051200345 cites W1585929623 @default.
• W2051200345 cites W1775749144 @default.
• W2051200345 cites W1966052869 @default.
• W2051200345 cites W1969805452 @default.
• W2051200345 cites W1975072002 @default.
• W2051200345 cites W1988951065 @default.
• W2051200345 cites W2000657292 @default.
• W2051200345 cites W2006451250 @default.
• W2051200345 cites W2010031749 @default.
• W2051200345 cites W2015686426 @default.
• W2051200345 cites W2020986622 @default.
• W2051200345 cites W2023161490 @default.
• W2051200345 cites W2027610535 @default.
• W2051200345 cites W2046784147 @default.
• W2051200345 cites W2074062322 @default.
• W2051200345 cites W2084606713 @default.
• W2051200345 cites W2093330438 @default.
• W2051200345 cites W2236202509 @default.
• W2051200345 cites W2291903346 @default.
• W2051200345 cites W2492650928 @default.
• W2051200345 cites W3140464090 @default.
• W2051200345 cites W937923706 @default.
• W2051200345 cites W982953202 @default.
• W2051200345 doi "https://doi.org/10.1016/0300-483x(86)90004-1" @default.
• W2051200345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2948297" @default.
• W2051200345 hasPublicationYear "1986" @default.
• W2051200345 type Work @default.
• W2051200345 sameAs 2051200345 @default.
• W2051200345 citedByCount "26" @default.
• W2051200345 countsByYear W20512003452012 @default.
• W2051200345 countsByYear W20512003452013 @default.
• W2051200345 countsByYear W20512003452017 @default.
• W2051200345 countsByYear W20512003452023 @default.
• W2051200345 crossrefType "journal-article" @default.
• W2051200345 hasAuthorship W2051200345A5034578625 @default.
• W2051200345 hasAuthorship W2051200345A5054230557 @default.
• W2051200345 hasAuthorship W2051200345A5063473062 @default.
• W2051200345 hasAuthorship W2051200345A5087210147 @default.
• W2051200345 hasConcept C181199279 @default.
• W2051200345 hasConcept C182215343 @default.
• W2051200345 hasConcept C185592680 @default.
• W2051200345 hasConcept C23265538 @default.
• W2051200345 hasConcept C24840226 @default.
• W2051200345 hasConcept C2779134199 @default.
• W2051200345 hasConcept C2781330172 @default.
• W2051200345 hasConcept C28859421 @default.
• W2051200345 hasConcept C3020377403 @default.
• W2051200345 hasConcept C55493867 @default.
• W2051200345 hasConcept C57600042 @default.
• W2051200345 hasConcept C59822182 @default.
• W2051200345 hasConcept C86803240 @default.
• W2051200345 hasConcept C87644729 @default.
• W2051200345 hasConceptScore W2051200345C181199279 @default.
• W2051200345 hasConceptScore W2051200345C182215343 @default.
• W2051200345 hasConceptScore W2051200345C185592680 @default.
• W2051200345 hasConceptScore W2051200345C23265538 @default.
• W2051200345 hasConceptScore W2051200345C24840226 @default.
• W2051200345 hasConceptScore W2051200345C2779134199 @default.
• W2051200345 hasConceptScore W2051200345C2781330172 @default.
• W2051200345 hasConceptScore W2051200345C28859421 @default.
• W2051200345 hasConceptScore W2051200345C3020377403 @default.
• W2051200345 hasConceptScore W2051200345C55493867 @default.
• W2051200345 hasConceptScore W2051200345C57600042 @default.
• W2051200345 hasConceptScore W2051200345C59822182 @default.
• W2051200345 hasConceptScore W2051200345C86803240 @default.
• W2051200345 hasConceptScore W2051200345C87644729 @default.
• W2051200345 hasIssue "2-3" @default.
• W2051200345 hasLocation W20512003451 @default.
• W2051200345 hasLocation W20512003452 @default.
• W2051200345 hasOpenAccess W2051200345 @default.
• W2051200345 hasPrimaryLocation W20512003451 @default.
• W2051200345 hasRelatedWork W1980515769 @default.
• W2051200345 hasRelatedWork W1992078446 @default.
• W2051200345 hasRelatedWork W2036023480 @default.
• W2051200345 hasRelatedWork W2074527668 @default.
• W2051200345 hasRelatedWork W2092636223 @default.
• W2051200345 hasRelatedWork W2143252519 @default.
• W2051200345 hasRelatedWork W2327274956 @default.
• W2051200345 hasRelatedWork W2330851722 @default.
• W2051200345 hasRelatedWork W2413760967 @default.
• W2051200345 hasRelatedWork W2440302835 @default.
• W2051200345 hasVolume "42" @default.
• W2051200345 isParatext "false" @default.

• next