FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051200539> ?p ?o ?g. }

• W2051200539 endingPage "918" @default.
• W2051200539 startingPage "909" @default.
• W2051200539 abstract "Abstract Early studies on dietary mutagenesis were mostly observational, with large numbers of potential dietary mutagens being identified from every conceivable dietary source. These included known dietary carcinogens such as aflatoxin B1 and benzo[a]pyrene, and hitherto unrecognized dietary mutagens, such as the pyrolysis products formed during the heating of proteinaceous materials (heterocyclic amines). The 1993 evaluation of 2‐amino‐3‐methyl‐3H‐imidazo(4,5‐j)quinoline as a probable human carcinogen by the International Agency for Research on Cancer was a landmark, as this was done in the absence of specific human carcinogenicity data, and strongly influenced by mutagenicity test data. In the 21st century, the field has moved from the identification of more and more mutagens, to molecular epidemiologic approaches that not only show a mutagenic effect but also seek to link it to a dietary (or environmental) cause. Effects of diet in stimulating chronic inflammation may lead to reactive species and thereby mutation as a secondary consequence, while dietary deficiencies and nutrient imbalances may be strong sources of mutagenesis. Recognition of the roles of nutrients in cell signaling processes and control of microRNAs suggest major influences on gene expression, in the absence of permanent DNA changes. Genome‐wide association studies have highlighted new pathways such as JAK/STAT signaling that profoundly influence genomic instability and responses to dietary mutagens. With improved methodologies for DNA sequencing and epigenetic changes, it is time to apply more sophisticated approaches to recognizing and proving the role of diet as a primary modulator of mutagenesis in humans. Environ. Mol. Mutagen., 2010. © 2010 Wiley‐Liss, Inc." @default.
• W2051200539 created "2016-06-24" @default.
• W2051200539 creator A5041435505 @default.
• W2051200539 date "2010-08-25" @default.
• W2051200539 modified "2023-10-17" @default.
• W2051200539 title "Dietary influences on mutagenesis—Where is this field going?" @default.
• W2051200539 cites W1619778662 @default.
• W2051200539 cites W1629787209 @default.
• W2051200539 cites W1963890672 @default.
• W2051200539 cites W1967189039 @default.
• W2051200539 cites W1967654566 @default.
• W2051200539 cites W1968094383 @default.
• W2051200539 cites W1971467516 @default.
• W2051200539 cites W1971774772 @default.
• W2051200539 cites W1973195696 @default.
• W2051200539 cites W1975391560 @default.
• W2051200539 cites W1979497965 @default.
• W2051200539 cites W1990863885 @default.
• W2051200539 cites W1992108302 @default.
• W2051200539 cites W1996105980 @default.
• W2051200539 cites W2001628109 @default.
• W2051200539 cites W2002546431 @default.
• W2051200539 cites W2003822832 @default.
• W2051200539 cites W2004678494 @default.
• W2051200539 cites W2004971707 @default.
• W2051200539 cites W2008368893 @default.
• W2051200539 cites W2018452213 @default.
• W2051200539 cites W2025613531 @default.
• W2051200539 cites W2026749159 @default.
• W2051200539 cites W2030885185 @default.
• W2051200539 cites W2031025087 @default.
• W2051200539 cites W2040703198 @default.
• W2051200539 cites W2041843352 @default.
• W2051200539 cites W2049669472 @default.
• W2051200539 cites W2050597647 @default.
• W2051200539 cites W2052371986 @default.
• W2051200539 cites W2057290105 @default.
• W2051200539 cites W2059471906 @default.
• W2051200539 cites W2066977080 @default.
• W2051200539 cites W2067127457 @default.
• W2051200539 cites W2068022035 @default.
• W2051200539 cites W2068354895 @default.
• W2051200539 cites W2075982593 @default.
• W2051200539 cites W2077478306 @default.
• W2051200539 cites W2081093364 @default.
• W2051200539 cites W2081335849 @default.
• W2051200539 cites W2082559953 @default.
• W2051200539 cites W2092781242 @default.
• W2051200539 cites W2093016546 @default.
• W2051200539 cites W2094605499 @default.
• W2051200539 cites W2095556565 @default.
• W2051200539 cites W2104589766 @default.
• W2051200539 cites W2104890139 @default.
• W2051200539 cites W2108998376 @default.
• W2051200539 cites W2110053345 @default.
• W2051200539 cites W2120156188 @default.
• W2051200539 cites W2125215178 @default.
• W2051200539 cites W2130114179 @default.
• W2051200539 cites W2143827266 @default.
• W2051200539 cites W2144940576 @default.
• W2051200539 cites W2149526874 @default.
• W2051200539 cites W2160956431 @default.
• W2051200539 cites W2172541372 @default.
• W2051200539 cites W2174562327 @default.
• W2051200539 cites W2180414713 @default.
• W2051200539 cites W2215622351 @default.
• W2051200539 cites W2329180650 @default.
• W2051200539 cites W2397329233 @default.
• W2051200539 cites W2614442853 @default.
• W2051200539 cites W2746558472 @default.
• W2051200539 cites W63811975 @default.
• W2051200539 doi "https://doi.org/10.1002/em.20594" @default.
• W2051200539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20740647" @default.
• W2051200539 hasPublicationYear "2010" @default.
• W2051200539 type Work @default.
• W2051200539 sameAs 2051200539 @default.
• W2051200539 citedByCount "16" @default.
• W2051200539 countsByYear W20512005392012 @default.
• W2051200539 countsByYear W20512005392013 @default.
• W2051200539 countsByYear W20512005392014 @default.
• W2051200539 countsByYear W20512005392017 @default.
• W2051200539 countsByYear W20512005392018 @default.
• W2051200539 crossrefType "journal-article" @default.
• W2051200539 hasAuthorship W2051200539A5041435505 @default.
• W2051200539 hasConcept C104317684 @default.
• W2051200539 hasConcept C114246631 @default.
• W2051200539 hasConcept C143425029 @default.
• W2051200539 hasConcept C16318435 @default.
• W2051200539 hasConcept C2776639595 @default.
• W2051200539 hasConcept C41091548 @default.
• W2051200539 hasConcept C501734568 @default.
• W2051200539 hasConcept C54355233 @default.
• W2051200539 hasConcept C552990157 @default.
• W2051200539 hasConcept C86803240 @default.
• W2051200539 hasConcept C97633540 @default.
• W2051200539 hasConceptScore W2051200539C104317684 @default.
• W2051200539 hasConceptScore W2051200539C114246631 @default.
• W2051200539 hasConceptScore W2051200539C143425029 @default.

• next