FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051203009> ?p ?o ?g. }

• W2051203009 endingPage "43" @default.
• W2051203009 startingPage "333" @default.
• W2051203009 abstract "Puerarin possesses a wide spectrum of biological activities including ameliorating effects on blood stasis, but the definite mechanism of this effect is still not known. In this study, a (1)H NMR-based plasma and urinary metabonomic approach was applied to comprehensively and holistically investigate the therapeutic effects of puerarin on blood stasis and its underlying mechanisms. Puerarin was injected intraperitoneally once daily for consecutive 7 days. The blood stasis rat model was established by placing the rats in ice-cold water during the time interval between two injections of adrenaline. With pattern recognition analysis, a clear separation of blood stasis model group and healthy control group was achieved and puerarin pretreatment group was located much closer to the control group than the model group, which was consistent with results of hemorheology studies. 15 and 10 potential biomarkers associated with blood stasis in plasma and urine, respectively, which were mainly involved in energy metabolism, lipid and membrane metabolisms, amino acid metabolism and gut microbiota metabolism, were identified. Puerarin could prevent blood stasis through partially regulating the disturbed metabolic pathways. This work highlights that metabonomics is a valuable tool for studying the essence of blood stasis as well as evaluating the efficacy of the corresponding drug treatment." @default.
• W2051203009 created "2016-06-24" @default.
• W2051203009 creator A5020542151 @default.
• W2051203009 creator A5025330487 @default.
• W2051203009 creator A5058587136 @default.
• W2051203009 creator A5078474296 @default.
• W2051203009 creator A5085643062 @default.
• W2051203009 creator A5091614852 @default.
• W2051203009 date "2015-03-15" @default.
• W2051203009 modified "2023-10-16" @default.
• W2051203009 title "Intervention effects of puerarin on blood stasis in rats revealed by a (1)H NMR-based metabonomic approach." @default.
• W2051203009 cites W1498599153 @default.
• W2051203009 cites W1558352361 @default.
• W2051203009 cites W1968813633 @default.
• W2051203009 cites W1968963326 @default.
• W2051203009 cites W1970415998 @default.
• W2051203009 cites W1976762598 @default.
• W2051203009 cites W1988871656 @default.
• W2051203009 cites W1991812341 @default.
• W2051203009 cites W1993196325 @default.
• W2051203009 cites W2013607204 @default.
• W2051203009 cites W2021242983 @default.
• W2051203009 cites W2021246671 @default.
• W2051203009 cites W2026074001 @default.
• W2051203009 cites W2031131414 @default.
• W2051203009 cites W2032031049 @default.
• W2051203009 cites W2048192140 @default.
• W2051203009 cites W2070296553 @default.
• W2051203009 cites W2078485629 @default.
• W2051203009 cites W2101976171 @default.
• W2051203009 cites W2134017403 @default.
• W2051203009 cites W2162234541 @default.
• W2051203009 doi "https://doi.org/10.1016/j.phymed.2015.01.006" @default.
• W2051203009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25837270" @default.
• W2051203009 hasPublicationYear "2015" @default.
• W2051203009 type Work @default.
• W2051203009 sameAs 2051203009 @default.
• W2051203009 citedByCount "26" @default.
• W2051203009 countsByYear W20512030092016 @default.
• W2051203009 countsByYear W20512030092017 @default.
• W2051203009 countsByYear W20512030092018 @default.
• W2051203009 countsByYear W20512030092019 @default.
• W2051203009 countsByYear W20512030092020 @default.
• W2051203009 countsByYear W20512030092021 @default.
• W2051203009 countsByYear W20512030092022 @default.
• W2051203009 crossrefType "journal-article" @default.
• W2051203009 hasAuthorship W2051203009A5020542151 @default.
• W2051203009 hasAuthorship W2051203009A5025330487 @default.
• W2051203009 hasAuthorship W2051203009A5058587136 @default.
• W2051203009 hasAuthorship W2051203009A5078474296 @default.
• W2051203009 hasAuthorship W2051203009A5085643062 @default.
• W2051203009 hasAuthorship W2051203009A5091614852 @default.
• W2051203009 hasConcept C126322002 @default.
• W2051203009 hasConcept C142724271 @default.
• W2051203009 hasConcept C185592680 @default.
• W2051203009 hasConcept C188947578 @default.
• W2051203009 hasConcept C204787440 @default.
• W2051203009 hasConcept C2776379591 @default.
• W2051203009 hasConcept C2778356392 @default.
• W2051203009 hasConcept C2780026642 @default.
• W2051203009 hasConcept C4733338 @default.
• W2051203009 hasConcept C62231903 @default.
• W2051203009 hasConcept C71924100 @default.
• W2051203009 hasConcept C78520924 @default.
• W2051203009 hasConcept C98274493 @default.
• W2051203009 hasConceptScore W2051203009C126322002 @default.
• W2051203009 hasConceptScore W2051203009C142724271 @default.
• W2051203009 hasConceptScore W2051203009C185592680 @default.
• W2051203009 hasConceptScore W2051203009C188947578 @default.
• W2051203009 hasConceptScore W2051203009C204787440 @default.
• W2051203009 hasConceptScore W2051203009C2776379591 @default.
• W2051203009 hasConceptScore W2051203009C2778356392 @default.
• W2051203009 hasConceptScore W2051203009C2780026642 @default.
• W2051203009 hasConceptScore W2051203009C4733338 @default.
• W2051203009 hasConceptScore W2051203009C62231903 @default.
• W2051203009 hasConceptScore W2051203009C71924100 @default.
• W2051203009 hasConceptScore W2051203009C78520924 @default.
• W2051203009 hasConceptScore W2051203009C98274493 @default.
• W2051203009 hasFunder F4320321001 @default.
• W2051203009 hasIssue "3" @default.
• W2051203009 hasLocation W20512030091 @default.
• W2051203009 hasLocation W20512030092 @default.
• W2051203009 hasOpenAccess W2051203009 @default.
• W2051203009 hasPrimaryLocation W20512030091 @default.
• W2051203009 hasRelatedWork W2051203009 @default.
• W2051203009 hasRelatedWork W2351814234 @default.
• W2051203009 hasRelatedWork W2357643417 @default.
• W2051203009 hasRelatedWork W2364506945 @default.
• W2051203009 hasRelatedWork W2371966035 @default.
• W2051203009 hasRelatedWork W2374784894 @default.
• W2051203009 hasRelatedWork W2375721225 @default.
• W2051203009 hasRelatedWork W2375970370 @default.
• W2051203009 hasRelatedWork W2381891021 @default.
• W2051203009 hasRelatedWork W2464549863 @default.
• W2051203009 hasVolume "22" @default.
• W2051203009 isParatext "false" @default.
• W2051203009 isRetracted "false" @default.
• W2051203009 magId "2051203009" @default.

• next