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- W2051205466 abstract "Case report An 89 year old woman had a two-month history of vaginal bleeding. Vaginal ultrasound examination showed an expanded endometrium. An outpatient endometrial biopsy was performed, which showed a moderately differentiated grade 2 endometrioid endometrial adenocarcinoma. Magnetic resonance imaging suggested that the tumour was minimally invasive and confined to the uterus (Fig. 1). The woman had limited exercise tolerance due to long-standing heart disease. Echocardiology confirmed moderate aortic stenosis. A cardiologist estimated that the chances of her surviving a general anaesthetic would be slightly greater than 50%. Several treatment options were discussed with the woman and her family. No treatment was rejected because the vaginal bleeding was increasing and was distressing for the woman and her family. Palliative treatment with radiotherapy and progesterone were also considered but rejected by the woman and her family. Therapeutic microwave ablation of the tumour was proposed. The Royal United Hospital Research Ethics Committee considered an emergency proposal to treat the woman’s minimally invasive endometrial carcinoma with microwave endometrial ablation. The Committee was satisfied that the woman and her family understood that this technique was entirely experimental in the current context and that other treatment options had been considered but rejected. Approval was granted. Microwave ablation of the endometrium was performed using a local anaesthetic block to the cervix. The cervix was easily dilated and as much tumour as possible was aspirated with a 7-mm diameter suction curette from the uterine cavity, which measured 11 cm in length. Uneventful microwave endometrial ablation was then performed. The treatment lasted for 6 1 = 2 minutes and the entire cavity lining was ablated" @default.
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- W2051205466 date "2002-12-01" @default.
- W2051205466 modified "2023-09-25" @default.
- W2051205466 title "Successful microwave ablation of endometrial carcinoma" @default.
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- W2051205466 doi "https://doi.org/10.1046/j.1471-0528.2002.01081.x" @default.
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