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- W2051205719 abstract "Acute kidney injury following folate administration is characterized by a vascular remodeling that is initially proliferative but subsequently results in vascular endothelial loss. Interventions directed toward promoting endothelial growth may preserve vascular structure and therefore renal function. However, angiopoietin-1 therapy in the setting of folate-induced acute kidney injury resulted in an expanded fibrotic response despite apparent preservation of the vasculature, indicating that renal repair responses are complex and vascular-directed therapies should be approached with caution." @default.
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- W2051205719 date "2008-08-01" @default.
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- W2051205719 title "Challenges of targeting vascular stability in acute kidney injury" @default.
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- W2051205719 doi "https://doi.org/10.1038/ki.2008.243" @default.
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