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- W2051207142 abstract "Fig. 1. FL dose–response of CYP1 enzymatic activity as measured by in ovo EROD assay and cardiac deformities (120hpf). Killifish embryos were simultaneously exposed 24–120hpf to waterborne concentrations of 21g/L ethoxyresorufin and either DMSO (vehicle control, 0.03% v/v), FL (50–500g/L), and/or 100g/L BaP. (A) The increasing deformity score represents increasing severity of cardiac deformities (CD) (0 =normal; 1 =mild deformities; 2 = severe deformities (see Fig. 3). Data are represented as the average deformity score± SEM from three replicate experiments; n=25. In the KC population, there was a significant interaction effect of BaP, FL and population (p<0.01; non-parametric ANOVA). In ovo EROD data are represented as the average percentage of KC control induction± SEM from three replicate experiments; n=25. In the KC population, there was a significant interaction effect of FL, BaP, and population (p<0.01; non-parametric ANOVA). (B) No significant increases in deformities were observed in the ER embryos for any of the treatments examined. Relative to the KC controls, exposure to FL had no significant effect on EROD induction in the ER embryos, either in the presence or absence of BaP. No significant increases in deformities were observed in the ER embryos for any of the treatments examined." @default.
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- W2051207142 date "2010-09-01" @default.
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- W2051207142 title "Erratum to “Effect of CYP1A inhibition on the biotransformation of benzo[a]pyrene in two populations of Fundulus heteroclitus with different exposure histories” [Aquat. Toxicol. 92 (2009) 195–201]" @default.
- W2051207142 doi "https://doi.org/10.1016/j.aquatox.2010.07.011" @default.
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