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- W2051209224 abstract "Thirty years ago, the discriminant-function test (the ratio of urinary androgen: glucocorticoids) was developed as a marker for women who subsequently developed breast cancer. At that time, it was not clear why this test had a predictive value, but recent research has suggested that androgens and glucocorticoids may have a crucial role in regulating cytokine production by Th1/Th2 cells. Decreased production of the adrenal androgen dehydroepiandrosterone and its sulphate is associated with the production of Th2-type cytokines, some of which have been shown to stimulate markedly the activities of the enzymes that are involved in oestrogen synthesis in breast-cancer cells." @default.
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- W2051209224 title "The discriminant-function test: a marker of Th1/Th2 cell cytokine secretion and breast tumour oestrogen synthesis" @default.
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- W2051209224 doi "https://doi.org/10.1016/s1357-4310(95)92435-3" @default.
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