Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051211511> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2051211511 abstract "Dietary supplementation with beta-carotene at 30 mg/day results in an increased serum trans-retinoic acid concentration in patients with a prior colonic polyp. In a number of human cell lines, trans-retinoic acid upregulates c-myc mRNA expression in colonic mucosa by reverse transcription polymerase chain reaction and correlated the results with serum concentrations of all-trans- (ATRA), 13-cis-(13-cRA), and total retinoic acid. Serum and colonic biopsy samples were obtained before and 90 days after administration of a placebo (n = 7) or 30 mg of beta-carotene (n = 5) daily. An increase in c-myc expression after supplementation was observed in 6 of 12 subjects, but 5 of these 6 subjects had decreased total serum retinoic acid concentration and 4 had decreased ATRA concentration. In addition, five of the six subjects with increased c-myc expression had received a placebo. Conversely, c-myc expression was increased in only two of five paired samples from subjects whose total serum retinoic acid concentration increased during the 90-day supplementation period. We conclude that c-myc expression is not correlated with ATRA, 13-cRA, or total retinoic acid concentration in vivo and that increased serum retinoic acid secondary to increased tissue beta-carotene is not sufficient to activate c-myc transcription." @default.
- W2051211511 created "2016-06-24" @default.
- W2051211511 creator A5058619881 @default.
- W2051211511 creator A5063992628 @default.
- W2051211511 creator A5075533960 @default.
- W2051211511 creator A5078935486 @default.
- W2051211511 date "1997-01-01" @default.
- W2051211511 modified "2023-09-23" @default.
- W2051211511 title "Expression ofc‐mycin human colonic tissue in response to β‐carotene supplementation" @default.
- W2051211511 cites W1502825258 @default.
- W2051211511 cites W1525444530 @default.
- W2051211511 cites W1844513720 @default.
- W2051211511 cites W1974337294 @default.
- W2051211511 cites W197438496 @default.
- W2051211511 cites W2026299899 @default.
- W2051211511 cites W2055833846 @default.
- W2051211511 cites W2066521306 @default.
- W2051211511 cites W2073386386 @default.
- W2051211511 cites W2076429988 @default.
- W2051211511 cites W2153399329 @default.
- W2051211511 cites W2168731357 @default.
- W2051211511 cites W2175180803 @default.
- W2051211511 cites W2407345634 @default.
- W2051211511 cites W79317665 @default.
- W2051211511 doi "https://doi.org/10.1080/01635589709514565" @default.
- W2051211511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9290118" @default.
- W2051211511 hasPublicationYear "1997" @default.
- W2051211511 type Work @default.
- W2051211511 sameAs 2051211511 @default.
- W2051211511 citedByCount "1" @default.
- W2051211511 countsByYear W20512115112017 @default.
- W2051211511 crossrefType "journal-article" @default.
- W2051211511 hasAuthorship W2051211511A5058619881 @default.
- W2051211511 hasAuthorship W2051211511A5063992628 @default.
- W2051211511 hasAuthorship W2051211511A5075533960 @default.
- W2051211511 hasAuthorship W2051211511A5078935486 @default.
- W2051211511 hasConcept C104317684 @default.
- W2051211511 hasConcept C126322002 @default.
- W2051211511 hasConcept C134018914 @default.
- W2051211511 hasConcept C142724271 @default.
- W2051211511 hasConcept C150194340 @default.
- W2051211511 hasConcept C153911025 @default.
- W2051211511 hasConcept C185592680 @default.
- W2051211511 hasConcept C204787440 @default.
- W2051211511 hasConcept C27081682 @default.
- W2051211511 hasConcept C2776940978 @default.
- W2051211511 hasConcept C2776998673 @default.
- W2051211511 hasConcept C2779573558 @default.
- W2051211511 hasConcept C2779963572 @default.
- W2051211511 hasConcept C2781121885 @default.
- W2051211511 hasConcept C31903555 @default.
- W2051211511 hasConcept C4692481 @default.
- W2051211511 hasConcept C48023723 @default.
- W2051211511 hasConcept C55493867 @default.
- W2051211511 hasConcept C71924100 @default.
- W2051211511 hasConcept C86803240 @default.
- W2051211511 hasConceptScore W2051211511C104317684 @default.
- W2051211511 hasConceptScore W2051211511C126322002 @default.
- W2051211511 hasConceptScore W2051211511C134018914 @default.
- W2051211511 hasConceptScore W2051211511C142724271 @default.
- W2051211511 hasConceptScore W2051211511C150194340 @default.
- W2051211511 hasConceptScore W2051211511C153911025 @default.
- W2051211511 hasConceptScore W2051211511C185592680 @default.
- W2051211511 hasConceptScore W2051211511C204787440 @default.
- W2051211511 hasConceptScore W2051211511C27081682 @default.
- W2051211511 hasConceptScore W2051211511C2776940978 @default.
- W2051211511 hasConceptScore W2051211511C2776998673 @default.
- W2051211511 hasConceptScore W2051211511C2779573558 @default.
- W2051211511 hasConceptScore W2051211511C2779963572 @default.
- W2051211511 hasConceptScore W2051211511C2781121885 @default.
- W2051211511 hasConceptScore W2051211511C31903555 @default.
- W2051211511 hasConceptScore W2051211511C4692481 @default.
- W2051211511 hasConceptScore W2051211511C48023723 @default.
- W2051211511 hasConceptScore W2051211511C55493867 @default.
- W2051211511 hasConceptScore W2051211511C71924100 @default.
- W2051211511 hasConceptScore W2051211511C86803240 @default.
- W2051211511 hasLocation W20512115111 @default.
- W2051211511 hasLocation W20512115112 @default.
- W2051211511 hasOpenAccess W2051211511 @default.
- W2051211511 hasPrimaryLocation W20512115111 @default.
- W2051211511 hasRelatedWork W1581604820 @default.
- W2051211511 hasRelatedWork W1998601765 @default.
- W2051211511 hasRelatedWork W2011492525 @default.
- W2051211511 hasRelatedWork W2051211511 @default.
- W2051211511 hasRelatedWork W2057538020 @default.
- W2051211511 hasRelatedWork W2110972239 @default.
- W2051211511 hasRelatedWork W2149842075 @default.
- W2051211511 hasRelatedWork W2155400147 @default.
- W2051211511 hasRelatedWork W2316581151 @default.
- W2051211511 hasRelatedWork W2393359706 @default.
- W2051211511 isParatext "false" @default.
- W2051211511 isRetracted "false" @default.
- W2051211511 magId "2051211511" @default.
- W2051211511 workType "article" @default.