FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051211731> ?p ?o ?g. }

• W2051211731 endingPage "2601" @default.
• W2051211731 startingPage "2579" @default.
• W2051211731 abstract "Depolarization of the presynaptic terminal by current produced a postsynaptic potential (PSP) which increased with increasing presynaptic polarization and then reached a plateau. Iontophoretic injection of tetraethylammonium ions (TEA) into the presynaptic axon near the terminal produced a prolonged presynaptic spike. The resulting PSP is increased in size and its time course closely followed that of the presynaptic spike. The presynaptic fiber no longer exhibited rectification and strong depolarizations revealed that the PSP reached a maximum with about 110 mv depolarization. Further depolarization produced a decrease in PSP amplitude and finally transmission was blocked. However, a PSP then always appeared on withdrawal of the depolarizing current. Under the conditions of these experiments, the PSP could be considered a direct measure of transmitter release. Bathing the TEA-injected synapse with concentrations of tetrodotoxin (TTX) sufficient to block spike activity in both pre- and postsynaptic axons did not greatly modify postsynaptic electrogenesis. However, doubling TTX concentration reversibly blocked PSP. Thus the permeability changes to Na and K accompanying the spike do not appear necessary for transmitter release. Some other processes related to the level of presynaptic polarization must be involved to explain the data. The inhibition of transmitter release by strong depolarizations appears to be related to Ca action. A membrane Ca current may also be necessary for normal transmitter release." @default.
• W2051211731 created "2016-06-24" @default.
• W2051211731 creator A5020711579 @default.
• W2051211731 creator A5056369817 @default.
• W2051211731 creator A5088664933 @default.
• W2051211731 date "1967-12-01" @default.
• W2051211731 modified "2023-09-26" @default.
• W2051211731 title "Correlation of Transmitter Release with Membrane Properties of the Presynaptic Fiber of the Squid Giant Synapse" @default.
• W2051211731 cites W1537610306 @default.
• W2051211731 cites W1964015678 @default.
• W2051211731 cites W1967799654 @default.
• W2051211731 cites W1970308975 @default.
• W2051211731 cites W1985940938 @default.
• W2051211731 cites W1995143337 @default.
• W2051211731 cites W2002465055 @default.
• W2051211731 cites W2011459292 @default.
• W2051211731 cites W2023707571 @default.
• W2051211731 cites W2040970293 @default.
• W2051211731 cites W2061904925 @default.
• W2051211731 cites W2068692059 @default.
• W2051211731 cites W2075352227 @default.
• W2051211731 cites W2078068750 @default.
• W2051211731 cites W2094135432 @default.
• W2051211731 cites W2097462167 @default.
• W2051211731 cites W2104896617 @default.
• W2051211731 cites W2112072206 @default.
• W2051211731 cites W2131460277 @default.
• W2051211731 cites W2146601122 @default.
• W2051211731 cites W2168287507 @default.
• W2051211731 cites W2315360655 @default.
• W2051211731 cites W2326656947 @default.
• W2051211731 cites W2340255892 @default.
• W2051211731 cites W2398410876 @default.
• W2051211731 cites W2403596545 @default.
• W2051211731 cites W2405567655 @default.
• W2051211731 doi "https://doi.org/10.1085/jgp.50.11.2579" @default.
• W2051211731 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2225670" @default.
• W2051211731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4296572" @default.
• W2051211731 hasPublicationYear "1967" @default.
• W2051211731 type Work @default.
• W2051211731 sameAs 2051211731 @default.
• W2051211731 citedByCount "113" @default.
• W2051211731 countsByYear W20512117312016 @default.
• W2051211731 countsByYear W20512117312019 @default.
• W2051211731 crossrefType "journal-article" @default.
• W2051211731 hasAuthorship W2051211731A5020711579 @default.
• W2051211731 hasAuthorship W2051211731A5056369817 @default.
• W2051211731 hasAuthorship W2051211731A5088664933 @default.
• W2051211731 hasBestOaLocation W20512117311 @default.
• W2051211731 hasConcept C12554922 @default.
• W2051211731 hasConcept C127445978 @default.
• W2051211731 hasConcept C169760540 @default.
• W2051211731 hasConcept C170493617 @default.
• W2051211731 hasConcept C178790620 @default.
• W2051211731 hasConcept C181911157 @default.
• W2051211731 hasConcept C185592680 @default.
• W2051211731 hasConcept C197341189 @default.
• W2051211731 hasConcept C200170125 @default.
• W2051211731 hasConcept C2776741303 @default.
• W2051211731 hasConcept C2779530196 @default.
• W2051211731 hasConcept C2781295685 @default.
• W2051211731 hasConcept C4141045 @default.
• W2051211731 hasConcept C517785266 @default.
• W2051211731 hasConcept C55493867 @default.
• W2051211731 hasConcept C86803240 @default.
• W2051211731 hasConceptScore W2051211731C12554922 @default.
• W2051211731 hasConceptScore W2051211731C127445978 @default.
• W2051211731 hasConceptScore W2051211731C169760540 @default.
• W2051211731 hasConceptScore W2051211731C170493617 @default.
• W2051211731 hasConceptScore W2051211731C178790620 @default.
• W2051211731 hasConceptScore W2051211731C181911157 @default.
• W2051211731 hasConceptScore W2051211731C185592680 @default.
• W2051211731 hasConceptScore W2051211731C197341189 @default.
• W2051211731 hasConceptScore W2051211731C200170125 @default.
• W2051211731 hasConceptScore W2051211731C2776741303 @default.
• W2051211731 hasConceptScore W2051211731C2779530196 @default.
• W2051211731 hasConceptScore W2051211731C2781295685 @default.
• W2051211731 hasConceptScore W2051211731C4141045 @default.
• W2051211731 hasConceptScore W2051211731C517785266 @default.
• W2051211731 hasConceptScore W2051211731C55493867 @default.
• W2051211731 hasConceptScore W2051211731C86803240 @default.
• W2051211731 hasIssue "11" @default.
• W2051211731 hasLocation W20512117311 @default.
• W2051211731 hasLocation W20512117312 @default.
• W2051211731 hasLocation W20512117313 @default.
• W2051211731 hasLocation W20512117314 @default.
• W2051211731 hasOpenAccess W2051211731 @default.
• W2051211731 hasPrimaryLocation W20512117311 @default.
• W2051211731 hasRelatedWork W124273784 @default.
• W2051211731 hasRelatedWork W1978112166 @default.
• W2051211731 hasRelatedWork W2009437632 @default.
• W2051211731 hasRelatedWork W2023707571 @default.
• W2051211731 hasRelatedWork W2030542053 @default.
• W2051211731 hasRelatedWork W2051211731 @default.
• W2051211731 hasRelatedWork W2083622839 @default.
• W2051211731 hasRelatedWork W2269586762 @default.
• W2051211731 hasRelatedWork W2405297906 @default.
• W2051211731 hasRelatedWork W2422530719 @default.

• next