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- W2051214126 abstract "We studied the influence of sex hormones using the hormone-sensitive levator ani muscle as a model tissue and glucose-6-phosphate dehydrogenase as an indicator of hormone action. Injection of testosterone or estradiol cause a 50% increase in the specific activity of glucose-6-phosphate dehydrogenase. The effect was dose-dependent, and was maximal at a dose of 2.5mg/100g body weight. Estradiol increased glucose-6-phosphate dehydrogenase as early as 8 h after injection, while testosterone required 12 h. Injection of estradiol on 2 successive days increased enzyme activity by 80%. The effect of estradiol was abolished by actinomycin D, suggesting enzyme induction. The results indicate a direct effect of estrogen on striated muscle." @default.
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- W2051214126 date "1980-02-01" @default.
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- W2051214126 title "Effect of sex hormones on glucose-6-phosphate dehydrogenase in rat levator ani muscle" @default.
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- W2051214126 doi "https://doi.org/10.1016/0303-7207(80)90123-9" @default.
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