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• W2051214400 abstract "Culture supernatants of splenocytes from C57BL/6 mice were exposed to 0.3, 1.0, and 3.0 microg/ml cordycepin plus 3.0 microg/ml lipopolysaccharide (LPS) to investigate the effects of cordycepin (3'-deoxyadenosine) on the production of inflammatory cytokines. Co-administration of 3.0 microg/ml cordycepin with LPS in cultured murine spleen cells significantly diminished the expression of the inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 (IL-6) in a time-dependent manner. Expression of the inflammatory cytokine IL-17A was substantially down-regulated in a time- dependent manner at all cordycepin concentrations. These findings suggest that cordycepin down-regulates the immediate hypersensitivity reaction stimulated by LPS." @default.
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• W2051214400 date "2013-02-01" @default.
• W2051214400 modified "2023-09-25" @default.
• W2051214400 title "Effect of Cordycepin on the Expression of the Inflammatory Cytokines TNF-alpha, IL-6, and IL-17A in C57BL/6 Mice" @default.
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• W2051214400 doi "https://doi.org/10.4014/jmb.1211.11032" @default.
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