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- W2051215124 abstract "Postoperative pancreatic fistula remains the most common complication of pancreaticoduodenectomy (PD) and is potentially lethal. It contributes significantly to prolonged hospitalization and mortality. In this study, we introduced a new technical approach, a modified Roux-en-Y reconstruction and evaluated its safety and feasibility.We retrospectively reviewed the patients who had undergone PD with the modified Roux-en-Y reconstructive technique for periampullary malignancies from January 2011 to June 2012. The data on complications, hospital stay and outcomes after the modified Roux-en-Y reconstruction were analyzed.The reconstruction was performed in 171 patients, of whom 92 received pancreaticogastrostomy and 79 received pancreaticojejunostomy. The median duration of surgery was 4.0 hours (range 3.1-6.9) in all patients, and the median blood loss was 530 mL (range 200–2000). Sixty-nine patients were subjected to transfusions, with a median transfusion volume of 430 mL (range 200–1400). The median hospital stay of the patients was 14 days (range 11–38). Their operative mortality was zero and overall morbidity was 18.1% (31 patients). Only four patients (2.3%) developed pancreatic fistulas (grade A fistulas in two patients and grade B in two patients); no patients developed grade C fistula. None of the patients developed bile reflux gastritis.The modified Roux-en-Y reconstruction, which isolates biliary anastomosis from pancreatic, gastric or jejunal anastomosis, is a safe, reliable, and favorable technique. But it needs further investigation in randomized controlled trials.(Hepatobiliary Pancreat Dis Int 2014;13:649-653)" @default.
- W2051215124 created "2016-06-24" @default.
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- W2051215124 date "2011-08-01" @default.
- W2051215124 modified "2023-10-18" @default.
- W2051215124 title "Joint Liver Center run by UCLA and First Affiliated Hospital, Zhejiang University School of Medicine was established at Hangzhou, China" @default.
- W2051215124 doi "https://doi.org/10.1016/s1499-3872(11)60071-4" @default.
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