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- W2051216153 abstract "We investigated the effects of the energy signal on the reinforcing effects and palatability to fat in mice.To examine the effects of postingestive energy signal, mice were injected with 400 micromol/kg body mass of mercaptoacetate, a beta-oxidation blocker or with saline (control group). Reinforcing effects and palatability response were examined with the conditioned place preference and one-bottle tests, respectively.In conditioned place preference tests, the mercaptoacetate group exhibited reinforcing effects when offered a 40% sucrose solution, which is not metabolized by the beta-oxidation pathway, but not when offered 100% corn oil. The control group exhibited reinforcing effects when offered the sucrose solution and when offered corn oil. In one-bottle tests, the control group exhibited palatability to corn oil, but the mercaptoacetate group did not. Consumption of sucrose solution was identical for both groups.These results suggest that postingestive energy signal influences the reinforcing effects and palatability of fat." @default.
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- W2051216153 date "2006-04-01" @default.
- W2051216153 modified "2023-10-13" @default.
- W2051216153 title "Inhibition of fatty acid β-oxidation attenuates the reinforcing effects and palatability to fat" @default.
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- W2051216153 doi "https://doi.org/10.1016/j.nut.2005.10.002" @default.
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