Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051216513> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2051216513 endingPage "541" @default.
- W2051216513 startingPage "538" @default.
- W2051216513 abstract "Pro CCK was expressed in an L cell line engineered to express PC1 and the products secreted into the media were characterized by a combination of RIA, gel filtration and HPLC. PC1 released from L cells, cleaved pro CCK generating the amino terminal pro peptide. PC1 also generated a peptide which after carboxypeptidase B treatment, was detected with an antiserum specific for CCK Gly. Neither of these peptides was found in media from L cells expressing pro CCK alone. This CCK Gly immunoreactive peptide was similar in size to CCK 8, and after treatment with arylsulfatase and carboxypeptidase B, it co-eluted on HPLC with unsulfated CCK 8 Gly. These results agree with previous studies which support a role for PC1 in generation of CCK 8. This is the first demonstration that PC1 acting alone is able to cleave pro CCK liberating the amino terminal pro peptide and a glycine and arginine extended CCK 8 which is the immediate precursor of CCK 8 amide." @default.
- W2051216513 created "2016-06-24" @default.
- W2051216513 creator A5028849312 @default.
- W2051216513 creator A5040805579 @default.
- W2051216513 creator A5077735430 @default.
- W2051216513 date "1998-07-01" @default.
- W2051216513 modified "2023-10-14" @default.
- W2051216513 title "Prohormone Convertase 1 (PC1) When Expressed with Pro Cholecystokinin (Pro CCK) in L Cells Performs Three Endoproteolytic Cleavages Which Are Observed in Rat Brain and in CCK-Expressing Endocrine Cells in Culture, Including the Production of Glycine and Arginine Extended CCK8" @default.
- W2051216513 cites W1506771283 @default.
- W2051216513 cites W1659182807 @default.
- W2051216513 cites W1998631347 @default.
- W2051216513 cites W2000337400 @default.
- W2051216513 cites W2014159291 @default.
- W2051216513 cites W2029142800 @default.
- W2051216513 cites W2030185317 @default.
- W2051216513 cites W2034326835 @default.
- W2051216513 cites W2038013713 @default.
- W2051216513 cites W2058651387 @default.
- W2051216513 cites W2070287146 @default.
- W2051216513 cites W2117233902 @default.
- W2051216513 doi "https://doi.org/10.1006/bbrc.1998.9006" @default.
- W2051216513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9703961" @default.
- W2051216513 hasPublicationYear "1998" @default.
- W2051216513 type Work @default.
- W2051216513 sameAs 2051216513 @default.
- W2051216513 citedByCount "19" @default.
- W2051216513 countsByYear W20512165132012 @default.
- W2051216513 countsByYear W20512165132016 @default.
- W2051216513 countsByYear W20512165132019 @default.
- W2051216513 crossrefType "journal-article" @default.
- W2051216513 hasAuthorship W2051216513A5028849312 @default.
- W2051216513 hasAuthorship W2051216513A5040805579 @default.
- W2051216513 hasAuthorship W2051216513A5077735430 @default.
- W2051216513 hasConcept C103395026 @default.
- W2051216513 hasConcept C108477463 @default.
- W2051216513 hasConcept C118303440 @default.
- W2051216513 hasConcept C153911025 @default.
- W2051216513 hasConcept C170493617 @default.
- W2051216513 hasConcept C181199279 @default.
- W2051216513 hasConcept C185592680 @default.
- W2051216513 hasConcept C2777468819 @default.
- W2051216513 hasConcept C2777593968 @default.
- W2051216513 hasConcept C2777951760 @default.
- W2051216513 hasConcept C2779281246 @default.
- W2051216513 hasConcept C2780090379 @default.
- W2051216513 hasConcept C46699223 @default.
- W2051216513 hasConcept C515207424 @default.
- W2051216513 hasConcept C54355233 @default.
- W2051216513 hasConcept C55493867 @default.
- W2051216513 hasConcept C56191518 @default.
- W2051216513 hasConcept C71315377 @default.
- W2051216513 hasConcept C81885089 @default.
- W2051216513 hasConcept C86803240 @default.
- W2051216513 hasConceptScore W2051216513C103395026 @default.
- W2051216513 hasConceptScore W2051216513C108477463 @default.
- W2051216513 hasConceptScore W2051216513C118303440 @default.
- W2051216513 hasConceptScore W2051216513C153911025 @default.
- W2051216513 hasConceptScore W2051216513C170493617 @default.
- W2051216513 hasConceptScore W2051216513C181199279 @default.
- W2051216513 hasConceptScore W2051216513C185592680 @default.
- W2051216513 hasConceptScore W2051216513C2777468819 @default.
- W2051216513 hasConceptScore W2051216513C2777593968 @default.
- W2051216513 hasConceptScore W2051216513C2777951760 @default.
- W2051216513 hasConceptScore W2051216513C2779281246 @default.
- W2051216513 hasConceptScore W2051216513C2780090379 @default.
- W2051216513 hasConceptScore W2051216513C46699223 @default.
- W2051216513 hasConceptScore W2051216513C515207424 @default.
- W2051216513 hasConceptScore W2051216513C54355233 @default.
- W2051216513 hasConceptScore W2051216513C55493867 @default.
- W2051216513 hasConceptScore W2051216513C56191518 @default.
- W2051216513 hasConceptScore W2051216513C71315377 @default.
- W2051216513 hasConceptScore W2051216513C81885089 @default.
- W2051216513 hasConceptScore W2051216513C86803240 @default.
- W2051216513 hasIssue "3" @default.
- W2051216513 hasLocation W20512165131 @default.
- W2051216513 hasLocation W20512165132 @default.
- W2051216513 hasOpenAccess W2051216513 @default.
- W2051216513 hasPrimaryLocation W20512165131 @default.
- W2051216513 hasRelatedWork W177916421 @default.
- W2051216513 hasRelatedWork W1900896992 @default.
- W2051216513 hasRelatedWork W1986405955 @default.
- W2051216513 hasRelatedWork W2008256978 @default.
- W2051216513 hasRelatedWork W2026239208 @default.
- W2051216513 hasRelatedWork W2031378227 @default.
- W2051216513 hasRelatedWork W2051216513 @default.
- W2051216513 hasRelatedWork W2063086217 @default.
- W2051216513 hasRelatedWork W2155455744 @default.
- W2051216513 hasRelatedWork W2257861630 @default.
- W2051216513 hasVolume "248" @default.
- W2051216513 isParatext "false" @default.
- W2051216513 isRetracted "false" @default.
- W2051216513 magId "2051216513" @default.
- W2051216513 workType "article" @default.