Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051216777> ?p ?o ?g. }
- W2051216777 endingPage "10294" @default.
- W2051216777 startingPage "10281" @default.
- W2051216777 abstract "We recently described the synthesis of 1-benzyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-diones, new potent and selective A(3) adenosine receptor antagonists containing a xanthine core. The present work can be considered an extension of our SAR studies on related structures in which the effect of different kind of substitutions at the 1-, 3- and 8-positions has been evaluated in order to improve both the potency and the hydrophilicity of the originally synthesised molecules. The A(3) binding disposition of these compounds was also investigated through docking and 3D-QSAR studies." @default.
- W2051216777 created "2016-06-24" @default.
- W2051216777 creator A5003958577 @default.
- W2051216777 creator A5007328509 @default.
- W2051216777 creator A5010109904 @default.
- W2051216777 creator A5023303060 @default.
- W2051216777 creator A5033429648 @default.
- W2051216777 creator A5036528092 @default.
- W2051216777 creator A5041567500 @default.
- W2051216777 creator A5060836466 @default.
- W2051216777 creator A5063804577 @default.
- W2051216777 creator A5083330689 @default.
- W2051216777 date "2008-12-15" @default.
- W2051216777 modified "2023-10-08" @default.
- W2051216777 title "Structure–activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A3 adenosine receptor antagonists" @default.
- W2051216777 cites W127389605 @default.
- W2051216777 cites W1963725788 @default.
- W2051216777 cites W1975974159 @default.
- W2051216777 cites W1977134430 @default.
- W2051216777 cites W1977967950 @default.
- W2051216777 cites W1992245666 @default.
- W2051216777 cites W1995303317 @default.
- W2051216777 cites W2008744406 @default.
- W2051216777 cites W2012666355 @default.
- W2051216777 cites W2013795726 @default.
- W2051216777 cites W2014503315 @default.
- W2051216777 cites W2015257123 @default.
- W2051216777 cites W2017760245 @default.
- W2051216777 cites W2024444349 @default.
- W2051216777 cites W2034658253 @default.
- W2051216777 cites W2039613574 @default.
- W2051216777 cites W2043813981 @default.
- W2051216777 cites W2045001050 @default.
- W2051216777 cites W2051907947 @default.
- W2051216777 cites W2054945498 @default.
- W2051216777 cites W2061980917 @default.
- W2051216777 cites W2062155179 @default.
- W2051216777 cites W2064342065 @default.
- W2051216777 cites W2066553600 @default.
- W2051216777 cites W2074631079 @default.
- W2051216777 cites W2078602449 @default.
- W2051216777 cites W2081102609 @default.
- W2051216777 cites W2082299271 @default.
- W2051216777 cites W2085344783 @default.
- W2051216777 cites W2093822310 @default.
- W2051216777 cites W2094821240 @default.
- W2051216777 cites W2106861254 @default.
- W2051216777 cites W2128635872 @default.
- W2051216777 cites W2133722275 @default.
- W2051216777 cites W2134336527 @default.
- W2051216777 cites W2146718841 @default.
- W2051216777 cites W2156032902 @default.
- W2051216777 cites W2158534713 @default.
- W2051216777 cites W2161018896 @default.
- W2051216777 cites W2169920833 @default.
- W2051216777 cites W2171445380 @default.
- W2051216777 cites W2179325597 @default.
- W2051216777 cites W2184569728 @default.
- W2051216777 cites W2188146526 @default.
- W2051216777 cites W2330990400 @default.
- W2051216777 cites W2415704481 @default.
- W2051216777 cites W2415973538 @default.
- W2051216777 cites W2950960385 @default.
- W2051216777 cites W73520867 @default.
- W2051216777 doi "https://doi.org/10.1016/j.bmc.2008.10.049" @default.
- W2051216777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19006671" @default.
- W2051216777 hasPublicationYear "2008" @default.
- W2051216777 type Work @default.
- W2051216777 sameAs 2051216777 @default.
- W2051216777 citedByCount "13" @default.
- W2051216777 countsByYear W20512167772012 @default.
- W2051216777 countsByYear W20512167772013 @default.
- W2051216777 countsByYear W20512167772017 @default.
- W2051216777 countsByYear W20512167772022 @default.
- W2051216777 countsByYear W20512167772023 @default.
- W2051216777 crossrefType "journal-article" @default.
- W2051216777 hasAuthorship W2051216777A5003958577 @default.
- W2051216777 hasAuthorship W2051216777A5007328509 @default.
- W2051216777 hasAuthorship W2051216777A5010109904 @default.
- W2051216777 hasAuthorship W2051216777A5023303060 @default.
- W2051216777 hasAuthorship W2051216777A5033429648 @default.
- W2051216777 hasAuthorship W2051216777A5036528092 @default.
- W2051216777 hasAuthorship W2051216777A5041567500 @default.
- W2051216777 hasAuthorship W2051216777A5060836466 @default.
- W2051216777 hasAuthorship W2051216777A5063804577 @default.
- W2051216777 hasAuthorship W2051216777A5083330689 @default.
- W2051216777 hasConcept C114373084 @default.
- W2051216777 hasConcept C159110408 @default.
- W2051216777 hasConcept C164126121 @default.
- W2051216777 hasConcept C170493617 @default.
- W2051216777 hasConcept C178910836 @default.
- W2051216777 hasConcept C181199279 @default.
- W2051216777 hasConcept C185592680 @default.
- W2051216777 hasConcept C193042331 @default.
- W2051216777 hasConcept C202751555 @default.
- W2051216777 hasConcept C21951064 @default.
- W2051216777 hasConcept C24961977 @default.
- W2051216777 hasConcept C2776476023 @default.