Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051217109> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2051217109 endingPage "210" @default.
- W2051217109 startingPage "203" @default.
- W2051217109 abstract "Summary A new allele of one of the metallothionein genes of D. melanogaster , Mtn •3 , sheds light on the recent evolution of this gene. In comparison to the previously studied Mtn l allele found in Canton S, this new allele, Mtn •3 , produces a transcript that is 49 bases longer and 65–70 % less abundant. We detected Mtn •3 in several laboratory strains as well as in isofemale lines derived from natural populations. Sequence comparison showed that Mtn •3 differs from Mtn l in that it has: (a) base-pair substitution and an extra 49 bp-segment in the 3' untranslated region, (b) a substitution in the coding region that replaces the terminal Glu40 in Mtn l with Lys40, and (c) two base-pair substitutions in the promoter region. The Mtn •3 -type was detected in six species of the melanogaster group by restriction analysis, and this result was confirmed by sequencing the D. simulans Mtn gene. Thus Mtn •3 , which produces a less abundant transcript, appears to be the oldest of the two alleles. We also found that the duplications previously isolated from natural populations all derived from Mtn l , the more recent allele. Thus, two evolutionary steps: Mtn•3 to Mtn l and Mtn l to Dp ( Mtn l ), are accompanied by an overall 5- to 6-fold increase of RNA accumulation. The two changes seem to have occurred in non-African populations since Mtn•3 but not Mtn l was detected in our sample from tropical Africa, while Mtn l and Dp ( Mtn l ) are prevalent in European and North American samples." @default.
- W2051217109 created "2016-06-24" @default.
- W2051217109 creator A5003192190 @default.
- W2051217109 creator A5026589965 @default.
- W2051217109 creator A5027318002 @default.
- W2051217109 date "1991-12-01" @default.
- W2051217109 modified "2023-09-25" @default.
- W2051217109 title "Recent evolutionary history of the metallothionein gene<i>Mtn</i>in<i>Drosophila</i>" @default.
- W2051217109 cites W1573680303 @default.
- W2051217109 cites W1601882650 @default.
- W2051217109 cites W1895321601 @default.
- W2051217109 cites W1953578971 @default.
- W2051217109 cites W1967801205 @default.
- W2051217109 cites W1989520724 @default.
- W2051217109 cites W1990338025 @default.
- W2051217109 cites W2009310436 @default.
- W2051217109 cites W2014203502 @default.
- W2051217109 cites W2018989399 @default.
- W2051217109 cites W2021008729 @default.
- W2051217109 cites W2038586333 @default.
- W2051217109 cites W2045890708 @default.
- W2051217109 cites W2054491767 @default.
- W2051217109 cites W2059589993 @default.
- W2051217109 cites W2064286019 @default.
- W2051217109 cites W2089070950 @default.
- W2051217109 cites W2118124127 @default.
- W2051217109 cites W2123246938 @default.
- W2051217109 cites W2140543174 @default.
- W2051217109 cites W2165172658 @default.
- W2051217109 cites W4239333561 @default.
- W2051217109 cites W4250221563 @default.
- W2051217109 cites W2058441786 @default.
- W2051217109 doi "https://doi.org/10.1017/s0016672300029955" @default.
- W2051217109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1802803" @default.
- W2051217109 hasPublicationYear "1991" @default.
- W2051217109 type Work @default.
- W2051217109 sameAs 2051217109 @default.
- W2051217109 citedByCount "28" @default.
- W2051217109 countsByYear W20512171092013 @default.
- W2051217109 countsByYear W20512171092019 @default.
- W2051217109 countsByYear W20512171092021 @default.
- W2051217109 countsByYear W20512171092022 @default.
- W2051217109 crossrefType "journal-article" @default.
- W2051217109 hasAuthorship W2051217109A5003192190 @default.
- W2051217109 hasAuthorship W2051217109A5026589965 @default.
- W2051217109 hasAuthorship W2051217109A5027318002 @default.
- W2051217109 hasBestOaLocation W20512171091 @default.
- W2051217109 hasConcept C101762097 @default.
- W2051217109 hasConcept C104317684 @default.
- W2051217109 hasConcept C150194340 @default.
- W2051217109 hasConcept C153911025 @default.
- W2051217109 hasConcept C180754005 @default.
- W2051217109 hasConcept C2780104201 @default.
- W2051217109 hasConcept C54355233 @default.
- W2051217109 hasConcept C65888428 @default.
- W2051217109 hasConcept C86803240 @default.
- W2051217109 hasConcept C91779695 @default.
- W2051217109 hasConceptScore W2051217109C101762097 @default.
- W2051217109 hasConceptScore W2051217109C104317684 @default.
- W2051217109 hasConceptScore W2051217109C150194340 @default.
- W2051217109 hasConceptScore W2051217109C153911025 @default.
- W2051217109 hasConceptScore W2051217109C180754005 @default.
- W2051217109 hasConceptScore W2051217109C2780104201 @default.
- W2051217109 hasConceptScore W2051217109C54355233 @default.
- W2051217109 hasConceptScore W2051217109C65888428 @default.
- W2051217109 hasConceptScore W2051217109C86803240 @default.
- W2051217109 hasConceptScore W2051217109C91779695 @default.
- W2051217109 hasIssue "3" @default.
- W2051217109 hasLocation W20512171091 @default.
- W2051217109 hasLocation W20512171092 @default.
- W2051217109 hasOpenAccess W2051217109 @default.
- W2051217109 hasPrimaryLocation W20512171091 @default.
- W2051217109 hasRelatedWork W1010636863 @default.
- W2051217109 hasRelatedWork W1826910757 @default.
- W2051217109 hasRelatedWork W1972681927 @default.
- W2051217109 hasRelatedWork W1980317616 @default.
- W2051217109 hasRelatedWork W2057739827 @default.
- W2051217109 hasRelatedWork W2094508838 @default.
- W2051217109 hasRelatedWork W2101093449 @default.
- W2051217109 hasRelatedWork W2223919059 @default.
- W2051217109 hasRelatedWork W2308817069 @default.
- W2051217109 hasRelatedWork W4255798889 @default.
- W2051217109 hasVolume "58" @default.
- W2051217109 isParatext "false" @default.
- W2051217109 isRetracted "false" @default.
- W2051217109 magId "2051217109" @default.
- W2051217109 workType "article" @default.