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• W2051218026 abstract "It was recently shown that cellular turnover occurs within the human adipocyte population. Through three independent experimental approaches--dilution of an inducible histone 2B-green fluorescent protein (H2BGFP), labeling with the cell cycle marker Ki67 and incorporation of BrdU--we characterized the degree of cellular turnover in murine adipose tissue. We observed rapid turnover of the adipocyte population, finding that 4.8% of preadipocytes are replicating at any time and that between 1-5% of adipocytes are replaced each day. In light of these findings, we suggest that adipose tissue turnover represents a possible new avenue of therapeutic intervention against obesity." @default.
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• W2051218026 date "2011-03-02" @default.
• W2051218026 modified "2023-10-11" @default.
• W2051218026 title "Rapid Cellular Turnover in Adipose Tissue" @default.
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• W2051218026 doi "https://doi.org/10.1371/journal.pone.0017637" @default.
• W2051218026 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3047582" @default.
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