FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051218772> ?p ?o ?g. }

• W2051218772 abstract "Human γδ T cells expressing the Vγ9Vδ2 T cell receptor can induce maturation of dendritic cells (DC) into antigen-presenting cells (APC) and B cells into antibody-secreting plasma cells. Since B cells are capable of presenting antigens to T cells, we investigated if Vγ9Vδ2 T cells can influence antigen-presentation by these cells. We report that Vγ9Vδ2 T cells induced expression of CD86, HLA-DR, and CD40 by B cells and stimulated the release of IL-4, IL-6, TNF-α, and IgG, IgA, and IgM. Vγ9Vδ2 T cells also augmented the ability of B cells to stimulate proliferation but not IFN-γ or IL-4 release by alloreactive T cells. In contrast, Vγ9Vδ2 T cells induced expression of CD86 and HLA-DR and the release of IFN-γ, IL-6, and TNF-α by DC and these DC stimulated proliferation and IFN-γ production by conventional T cells. Furthermore, CD86, TNF-α, IFN-γ, and cell contact were found to be important in DC activation by Vγ9Vδ2 T cells but not in the activation of B cells. These data suggest that Vγ9Vδ2 T cells can induce maturation of B cells and DC into APC, but while they prime DC to stimulate T helper 1 (TH1) responses, they drive maturation of B cells into APC that can stimulate different T cell responses. Thus, Vγ9Vδ2 T cells can control different arms of the immune system through selective activation of B cells and DC in vitro, which may have important applications in immunotherapy and for vaccine adjuvants." @default.
• W2051218772 created "2016-06-24" @default.
• W2051218772 creator A5011497420 @default.
• W2051218772 creator A5079499350 @default.
• W2051218772 date "2014-12-19" @default.
• W2051218772 modified "2023-10-16" @default.
• W2051218772 title "Human Vδ2+ γδ T Cells Differentially Induce Maturation, Cytokine Production, and Alloreactive T Cell Stimulation by Dendritic Cells and B Cells" @default.
• W2051218772 cites W124239641 @default.
• W2051218772 cites W1512693074 @default.
• W2051218772 cites W1521274572 @default.
• W2051218772 cites W1538852380 @default.
• W2051218772 cites W1547450219 @default.
• W2051218772 cites W1764179577 @default.
• W2051218772 cites W1825609770 @default.
• W2051218772 cites W1944454646 @default.
• W2051218772 cites W1949793450 @default.
• W2051218772 cites W1971761379 @default.
• W2051218772 cites W1981756981 @default.
• W2051218772 cites W1984282453 @default.
• W2051218772 cites W1992697645 @default.
• W2051218772 cites W1992794673 @default.
• W2051218772 cites W1998299106 @default.
• W2051218772 cites W2002073873 @default.
• W2051218772 cites W2012636177 @default.
• W2051218772 cites W2012720624 @default.
• W2051218772 cites W2017312699 @default.
• W2051218772 cites W2018540827 @default.
• W2051218772 cites W2019182330 @default.
• W2051218772 cites W2021750455 @default.
• W2051218772 cites W2033877575 @default.
• W2051218772 cites W2038402399 @default.
• W2051218772 cites W2038574124 @default.
• W2051218772 cites W2051435999 @default.
• W2051218772 cites W2057730096 @default.
• W2051218772 cites W2060163534 @default.
• W2051218772 cites W2062372633 @default.
• W2051218772 cites W2063131740 @default.
• W2051218772 cites W2066013154 @default.
• W2051218772 cites W2073312795 @default.
• W2051218772 cites W2080478095 @default.
• W2051218772 cites W2084006363 @default.
• W2051218772 cites W2090046324 @default.
• W2051218772 cites W2109606712 @default.
• W2051218772 cites W2111220263 @default.
• W2051218772 cites W2112517102 @default.
• W2051218772 cites W2114307517 @default.
• W2051218772 cites W2114630456 @default.
• W2051218772 cites W2114915759 @default.
• W2051218772 cites W2122232311 @default.
• W2051218772 cites W2122582242 @default.
• W2051218772 cites W2127367385 @default.
• W2051218772 cites W2130546703 @default.
• W2051218772 cites W2135668977 @default.
• W2051218772 cites W2150060394 @default.
• W2051218772 cites W2153073920 @default.
• W2051218772 cites W2161354474 @default.
• W2051218772 cites W2167269208 @default.
• W2051218772 cites W2170417753 @default.
• W2051218772 cites W2172261775 @default.
• W2051218772 doi "https://doi.org/10.3389/fimmu.2014.00650" @default.
• W2051218772 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4271703" @default.
• W2051218772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25566261" @default.
• W2051218772 hasPublicationYear "2014" @default.
• W2051218772 type Work @default.
• W2051218772 sameAs 2051218772 @default.
• W2051218772 citedByCount "27" @default.
• W2051218772 countsByYear W20512187722015 @default.
• W2051218772 countsByYear W20512187722016 @default.
• W2051218772 countsByYear W20512187722017 @default.
• W2051218772 countsByYear W20512187722018 @default.
• W2051218772 countsByYear W20512187722019 @default.
• W2051218772 countsByYear W20512187722020 @default.
• W2051218772 countsByYear W20512187722021 @default.
• W2051218772 countsByYear W20512187722022 @default.
• W2051218772 countsByYear W20512187722023 @default.
• W2051218772 crossrefType "journal-article" @default.
• W2051218772 hasAuthorship W2051218772A5011497420 @default.
• W2051218772 hasAuthorship W2051218772A5079499350 @default.
• W2051218772 hasBestOaLocation W20512187721 @default.
• W2051218772 hasConcept C120642132 @default.
• W2051218772 hasConcept C129374314 @default.
• W2051218772 hasConcept C131665280 @default.
• W2051218772 hasConcept C139563560 @default.
• W2051218772 hasConcept C145558887 @default.
• W2051218772 hasConcept C147483822 @default.
• W2051218772 hasConcept C149532602 @default.
• W2051218772 hasConcept C154317977 @default.
• W2051218772 hasConcept C200180986 @default.
• W2051218772 hasConcept C202751555 @default.
• W2051218772 hasConcept C203014093 @default.
• W2051218772 hasConcept C2776090121 @default.
• W2051218772 hasConcept C2778297628 @default.
• W2051218772 hasConcept C2781101188 @default.
• W2051218772 hasConcept C39347974 @default.
• W2051218772 hasConcept C55493867 @default.
• W2051218772 hasConcept C67662055 @default.
• W2051218772 hasConcept C79484868 @default.
• W2051218772 hasConcept C83464605 @default.
• W2051218772 hasConcept C86803240 @default.
• W2051218772 hasConcept C8891405 @default.

• next