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- W2051222093 abstract "Extracorporeal life support (ECLS) has been used in this institution since 1988 and we reviewed our experience with its use in the management of massive pulmonary embolism (PE). John Gibbon first developed the heart-lung machine in the early 1950's, motivated by the search to treat massive pulmonary embolism. From January 1992 to July 2000, 15 patients were placed on extracorporeal support for massive PE. All the patients were on pressors, acidotic and hypoxic at the time of the institution of support, 12/15 were in shock despite all efforts and 9/15 were in cardiac arrest or had just been resuscitated. Five patients were trauma patients, five had recent surgeries, and of the 15 patients, seven were found to have hypercoagulable disorders. Thirteen of 15 were cannulated emergently for veno-arterial bypass, 2/15 were. placed on veno-venous bypass, and the average duration of support for survivors was 5 days ± 3 days, ranging from 0.25 to 11 days. Emboli resolved with anticoagulation in 12/15 patients, and 3/15 underwent surgical pulmonary embolectomy. Overall survival was 73% (11/15). During this time period 14 other patients were referred for ECLS because of presumed or proven massive PE, but ECLS was not instituted for various reasons other than cardiac instability. Thirteen of the 14 died. We conclude that ECLS resulted in a dramatic improvement in the prognosis of an otherwise near-fatal condition, and should be considered in the algorithm for management of massive pulmonary embolism in an unstable patient. Gibbon was right." @default.
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- W2051222093 date "2001-03-01" @default.
- W2051222093 modified "2023-09-23" @default.
- W2051222093 title "EXTRACORPOREAL LIFE SUPPORT FOR MASSIVE PULMONARY EMBOLISM" @default.
- W2051222093 doi "https://doi.org/10.1097/00002480-200103000-00178" @default.
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