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• W2051223395 abstract "Listeria monocytogenes is a food-borne Gram-positive bacterium that is responsible for a variety of infections (worldwide) annually. The organism is able to survive a variety of environmental conditions and stresses, however, the mechanisms by which L. monocytogenes adapts to environmental change are yet to be fully elucidated. An understanding of the mechanism(s) by which L. monocytogenes survives unfavourable environmental conditions will aid in developing new food processing methods to control the organism in foodstuffs. We have utilized a proteomic approach to investigate the response of L. monocytogenes batch cultures to the transition from exponential to stationary growth phase. Proteomic analysis showed that batch cultures of L. monocytogenes perceived stress and began preparations for stationary phase much earlier (approximately A600 = 0.75, mid-exponential) than predicted by growth characteristics alone. Global analysis of the proteome revealed that the expression levels of more than 50% of all proteins observed changed significantly over a 7–9 h period during this transition phase. We have highlighted ten proteins in particular whose expression levels appear to be important in the early onset of the stationary phase. The significance of these findings in terms of functionality and the mechanistic picture are discussed." @default.
• W2051223395 created "2016-06-24" @default.
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• W2051223395 date "2003-07-23" @default.
• W2051223395 modified "2023-09-26" @default.
• W2051223395 title "Global changes in gene expression observed at the transition from growth to stationary phase in Listeria monocytogenes ScottA batch culture" @default.
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• W2051223395 doi "https://doi.org/10.1002/pmic.200300527" @default.
• W2051223395 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14730677" @default.
• W2051223395 hasPublicationYear "2003" @default.
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