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- W2051224250 abstract "Abstract The molecular forms and activities of ram DNA ligase have been investigated during spermatogenesis from the stage of early round spermatids to ejaculated spermatozoa. Through germ cell maturation, two consecutive forms of the enzyme (6S and 7S) have been found. The 6S form (DNA ligase II) is observed in primary and secondary spermatocyte, as well as in round spermatids. The 7S form (DNA ligase I) is present in elongated spermatids and in the sole round cell population with spermatogonia and young primary spermatocytes. In ram germ cells, DNA ligase I and DNA ligase II appear to be respectively associated with DNA replication repair. The absence of DNA ligase II associated with the absence of DNA repair in testicular and ejaculated spermatozoa might be related to male infertility." @default.
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- W2051224250 date "1982-10-01" @default.
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- W2051224250 title "Developmental changes of DNA ligase during ram spermatogenesis" @default.
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- W2051224250 doi "https://doi.org/10.1016/0014-4827(82)90224-5" @default.
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