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- W2051225627 abstract "A DNA-cellulose competition assay was used to study binding of glucocorticoid receptor complexes to two alpha 2u-globulin genes, RAP 01 and RAO 01. Two binding regions were found in RAP 01, one localized between bp -642 and -452, the other between -252 and -118 from the transcriptional initiation site. Only the second region was found in RAO 01. The binding affinity was comparable to that observed using a long terminal repeat fragment of mouse mammary tumor virus. Both regions contain sequences homologous to a 17-bp consensus proposed for the glucocorticoid receptor binding. Therefore, despite evidence that glucocorticoid induction of alpha 2u-globulin may be indirect, a direct action of the receptor in the 5'-upstream region of the genes cannot be excluded." @default.
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- W2051225627 date "1987-12-01" @default.
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- W2051225627 title "Glucocorticoid receptor binding to defined regions of α2 u-globulin genes" @default.
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- W2051225627 doi "https://doi.org/10.1016/0006-291x(87)90521-3" @default.
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