FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051225692> ?p ?o ?g. }

• W2051225692 endingPage "884" @default.
• W2051225692 startingPage "876" @default.
• W2051225692 abstract "Osteoporotic hip fractures represent a major public health problem associated with high human and economic costs. The anatomical variation of the tissue mineral density (TMD) and of the elastic constants in femoral neck cortical bone specimens is an important determinant of bone fragility. The purpose of this study was to show that a Synchrotron radiation microcomputed tomography system coupled with a multiscale biomechanical model allows the determination of the 3-D anatomical dependence of TMD and of the elastic constants (i.e. the mechanical properties of an anisotropic material) in human femoral neck. Bone specimens from the inferior femoral neck were obtained from 18 patients undergoing standard hemiarthroplasty. The specimens were imaged using 3-D synchrotron micro-computed tomography with a voxel size of 10.13 μm, leading to the determination of the anatomical distributions of porosity and TMD. The elastic properties of bone tissue were computed using a multiscale model. The model uses the experimental data obtained at the scale of several micrometers to estimate the components of the elastic tensor of bone at the scale of the organ. Statistical analysis (ANOVA) revealed a significant effect of the radial position on porosity and TMD and a significant effect of axial position on TMD only. Porosity was found to increase in the radial direction moving from the periosteum inwards (p < 10− 5). At any given distance from the periosteum, porosity does not vary noticeably along the bone axis. TMD was found to be significantly higher (p < 10− 5) in the periosteal region than in other bone locations and decreases from the periosteal to the endosteal region with an average slope of 10.05 g.cm− 3.m− 1, the decrease being faster in the porous part of the samples (average slope equal of 30.04 g.cm− 3.m− 1) than in dense cortical bone. TMD was found to decrease from the distal to the proximal part of the femur neck (average slope of 6.5 g.cm− 3.m− 1). Considering TMD variations in the radial direction induces weak changes of bone properties compared to constant TMD. TMD variations in the axial direction are responsible for a significant variation of elastic constants. These results demonstrate that the anatomical variations of TMD affect the bone elastic properties, which could be explained by the complex stress field in bone affecting bone remodeling. TMD spatial variations should be taken into account to properly describe the spatial heterogeneity of elastic coefficients of bone tissue at the organ scale." @default.
• W2051225692 created "2016-06-24" @default.
• W2051225692 creator A5003414812 @default.
• W2051225692 creator A5003931348 @default.
• W2051225692 creator A5006223188 @default.
• W2051225692 creator A5034060673 @default.
• W2051225692 creator A5034810603 @default.
• W2051225692 creator A5061057789 @default.
• W2051225692 creator A5075496055 @default.
• W2051225692 date "2012-04-01" @default.
• W2051225692 modified "2023-10-18" @default.
• W2051225692 title "Anatomical distribution of the degree of mineralization of bone tissue in human femoral neck: Impact on biomechanical properties" @default.
• W2051225692 cites W1964058537 @default.
• W2051225692 cites W1972173398 @default.
• W2051225692 cites W1974725047 @default.
• W2051225692 cites W1978519725 @default.
• W2051225692 cites W1995272666 @default.
• W2051225692 cites W1996767999 @default.
• W2051225692 cites W2000461506 @default.
• W2051225692 cites W2000948190 @default.
• W2051225692 cites W2001176484 @default.
• W2051225692 cites W2002528194 @default.
• W2051225692 cites W2003109294 @default.
• W2051225692 cites W2006090280 @default.
• W2051225692 cites W2007610014 @default.
• W2051225692 cites W2015313580 @default.
• W2051225692 cites W2020641822 @default.
• W2051225692 cites W2021693450 @default.
• W2051225692 cites W2028608421 @default.
• W2051225692 cites W2030777780 @default.
• W2051225692 cites W2032244293 @default.
• W2051225692 cites W2033375557 @default.
• W2051225692 cites W2043840576 @default.
• W2051225692 cites W2054150561 @default.
• W2051225692 cites W2055264824 @default.
• W2051225692 cites W2060398686 @default.
• W2051225692 cites W2066749771 @default.
• W2051225692 cites W2069406013 @default.
• W2051225692 cites W2074993293 @default.
• W2051225692 cites W2079507601 @default.
• W2051225692 cites W2085086344 @default.
• W2051225692 cites W2091445919 @default.
• W2051225692 cites W2092049076 @default.
• W2051225692 cites W2092501887 @default.
• W2051225692 cites W2105466215 @default.
• W2051225692 cites W2118226408 @default.
• W2051225692 cites W2119803079 @default.
• W2051225692 cites W2123506449 @default.
• W2051225692 cites W2130796365 @default.
• W2051225692 cites W2132551393 @default.
• W2051225692 cites W2148663720 @default.
• W2051225692 cites W2159775719 @default.
• W2051225692 cites W2162476583 @default.
• W2051225692 cites W2914774459 @default.
• W2051225692 cites W2119966126 @default.
• W2051225692 doi "https://doi.org/10.1016/j.bone.2011.12.020" @default.
• W2051225692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22245631" @default.
• W2051225692 hasPublicationYear "2012" @default.
• W2051225692 type Work @default.
• W2051225692 sameAs 2051225692 @default.
• W2051225692 citedByCount "40" @default.
• W2051225692 countsByYear W20512256922012 @default.
• W2051225692 countsByYear W20512256922013 @default.
• W2051225692 countsByYear W20512256922014 @default.
• W2051225692 countsByYear W20512256922015 @default.
• W2051225692 countsByYear W20512256922016 @default.
• W2051225692 countsByYear W20512256922017 @default.
• W2051225692 countsByYear W20512256922018 @default.
• W2051225692 countsByYear W20512256922019 @default.
• W2051225692 countsByYear W20512256922020 @default.
• W2051225692 countsByYear W20512256922022 @default.
• W2051225692 countsByYear W20512256922023 @default.
• W2051225692 crossrefType "journal-article" @default.
• W2051225692 hasAuthorship W2051225692A5003414812 @default.
• W2051225692 hasAuthorship W2051225692A5003931348 @default.
• W2051225692 hasAuthorship W2051225692A5006223188 @default.
• W2051225692 hasAuthorship W2051225692A5034060673 @default.
• W2051225692 hasAuthorship W2051225692A5034810603 @default.
• W2051225692 hasAuthorship W2051225692A5061057789 @default.
• W2051225692 hasAuthorship W2051225692A5075496055 @default.
• W2051225692 hasConcept C105702510 @default.
• W2051225692 hasConcept C126838900 @default.
• W2051225692 hasConcept C136229726 @default.
• W2051225692 hasConcept C142724271 @default.
• W2051225692 hasConcept C159985019 @default.
• W2051225692 hasConcept C192562407 @default.
• W2051225692 hasConcept C2775854910 @default.
• W2051225692 hasConcept C2776541429 @default.
• W2051225692 hasConcept C2777674748 @default.
• W2051225692 hasConcept C2778606738 @default.
• W2051225692 hasConcept C2781451080 @default.
• W2051225692 hasConcept C54170458 @default.
• W2051225692 hasConcept C6648577 @default.
• W2051225692 hasConcept C71924100 @default.
• W2051225692 hasConceptScore W2051225692C105702510 @default.
• W2051225692 hasConceptScore W2051225692C126838900 @default.
• W2051225692 hasConceptScore W2051225692C136229726 @default.
• W2051225692 hasConceptScore W2051225692C142724271 @default.

• next