FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051225771> ?p ?o ?g. }

• W2051225771 abstract "Therapeutic drug monitoring is now incorporated into the treatment guidelines of many countries. In this review, we describe the use and limitations of therapeutic drug monitoring, and how added benefit might accrue from integrating therapeutic drug monitoring with resistance testing in the form of inhibitory quotients.Although the unselected use of therapeutic drug monitoring in current (ritonavir-boosted) protease inhibitor or nonnucleoside reverse transcriptase inhibitor-containing regimens has yet to be established, therapeutic drug monitoring is likely to be useful in selected groups of patients, such as children, pregnant women, patients with malabsorption, or in specific clinical scenarios, such as liver impairment, drug interactions, suspected toxicity, assessing adherence or treatment failure. One problem with therapeutic drug monitoring is that efficacy targets relate mainly to drug-sensitive virus. Inhibitory quotients may be a better predictor of response in treatment-experienced patients.In this review, we discuss the different derivations of inhibitory quotients. Inhibitory quotients have been shown to be predictive of virological response in heavily pretreated patients receiving lopinavir, amprenavir, saquinavir, atazanavir and tipranavir. Lack of standardization and consensus on which inhibitory quotient to use are major factors which limit their introduction into clinical practice." @default.
• W2051225771 created "2016-06-24" @default.
• W2051225771 creator A5013690116 @default.
• W2051225771 creator A5041365930 @default.
• W2051225771 creator A5042249868 @default.
• W2051225771 date "2007-05-01" @default.
• W2051225771 modified "2023-09-26" @default.
• W2051225771 title "Combining resistance and pharmacology for optimum patient care" @default.
• W2051225771 cites W1973129764 @default.
• W2051225771 cites W1977156000 @default.
• W2051225771 cites W1985267067 @default.
• W2051225771 cites W1987126955 @default.
• W2051225771 cites W1992401855 @default.
• W2051225771 cites W1995687174 @default.
• W2051225771 cites W1998616088 @default.
• W2051225771 cites W2002977614 @default.
• W2051225771 cites W2008565853 @default.
• W2051225771 cites W2008579529 @default.
• W2051225771 cites W2014053790 @default.
• W2051225771 cites W2034273907 @default.
• W2051225771 cites W2040478046 @default.
• W2051225771 cites W2044932421 @default.
• W2051225771 cites W2052298260 @default.
• W2051225771 cites W2061577259 @default.
• W2051225771 cites W2063543191 @default.
• W2051225771 cites W2064510625 @default.
• W2051225771 cites W2064951444 @default.
• W2051225771 cites W2065855820 @default.
• W2051225771 cites W2070983157 @default.
• W2051225771 cites W2075068500 @default.
• W2051225771 cites W2082145199 @default.
• W2051225771 cites W2086783015 @default.
• W2051225771 cites W2096675880 @default.
• W2051225771 cites W2105737742 @default.
• W2051225771 cites W2106737113 @default.
• W2051225771 cites W2108013853 @default.
• W2051225771 cites W2112710992 @default.
• W2051225771 cites W2114652938 @default.
• W2051225771 cites W2115378753 @default.
• W2051225771 cites W2127961073 @default.
• W2051225771 cites W2131475321 @default.
• W2051225771 cites W2135892517 @default.
• W2051225771 cites W2140114084 @default.
• W2051225771 cites W2141400171 @default.
• W2051225771 cites W2141776019 @default.
• W2051225771 cites W2144905510 @default.
• W2051225771 cites W2151647473 @default.
• W2051225771 cites W2157310081 @default.
• W2051225771 cites W2163203978 @default.
• W2051225771 cites W2164373966 @default.
• W2051225771 cites W2170385855 @default.
• W2051225771 cites W2322921107 @default.
• W2051225771 cites W2328404965 @default.
• W2051225771 cites W2409710097 @default.
• W2051225771 cites W2413375126 @default.
• W2051225771 cites W2003206770 @default.
• W2051225771 cites W2068973269 @default.
• W2051225771 doi "https://doi.org/10.1097/coh.0b013e3280f31d27" @default.
• W2051225771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19372882" @default.
• W2051225771 hasPublicationYear "2007" @default.
• W2051225771 type Work @default.
• W2051225771 sameAs 2051225771 @default.
• W2051225771 citedByCount "5" @default.
• W2051225771 countsByYear W20512257712020 @default.
• W2051225771 crossrefType "journal-article" @default.
• W2051225771 hasAuthorship W2051225771A5013690116 @default.
• W2051225771 hasAuthorship W2051225771A5041365930 @default.
• W2051225771 hasAuthorship W2051225771A5042249868 @default.
• W2051225771 hasConcept C114851261 @default.
• W2051225771 hasConcept C142462285 @default.
• W2051225771 hasConcept C177713679 @default.
• W2051225771 hasConcept C181199279 @default.
• W2051225771 hasConcept C203014093 @default.
• W2051225771 hasConcept C2776714187 @default.
• W2051225771 hasConcept C2776937687 @default.
• W2051225771 hasConcept C2777182164 @default.
• W2051225771 hasConcept C2777363262 @default.
• W2051225771 hasConcept C2777583353 @default.
• W2051225771 hasConcept C2778414717 @default.
• W2051225771 hasConcept C2779298103 @default.
• W2051225771 hasConcept C2780035454 @default.
• W2051225771 hasConcept C2780272996 @default.
• W2051225771 hasConcept C2993143319 @default.
• W2051225771 hasConcept C3013748606 @default.
• W2051225771 hasConcept C55493867 @default.
• W2051225771 hasConcept C71924100 @default.
• W2051225771 hasConcept C86803240 @default.
• W2051225771 hasConcept C89423630 @default.
• W2051225771 hasConcept C98274493 @default.
• W2051225771 hasConceptScore W2051225771C114851261 @default.
• W2051225771 hasConceptScore W2051225771C142462285 @default.
• W2051225771 hasConceptScore W2051225771C177713679 @default.
• W2051225771 hasConceptScore W2051225771C181199279 @default.
• W2051225771 hasConceptScore W2051225771C203014093 @default.
• W2051225771 hasConceptScore W2051225771C2776714187 @default.
• W2051225771 hasConceptScore W2051225771C2776937687 @default.
• W2051225771 hasConceptScore W2051225771C2777182164 @default.
• W2051225771 hasConceptScore W2051225771C2777363262 @default.
• W2051225771 hasConceptScore W2051225771C2777583353 @default.
• W2051225771 hasConceptScore W2051225771C2778414717 @default.

• next