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- W2051226166 abstract "362 blood-transfusion recipients, whose sera were initially negative for hepatitis-B antigen (HBsAg), were prospectively followed for clinical and serological evidence of exposure to hepatitis-B virus (H.B.V.) and for the development of hepatitis unrelated to H.B.V. None of the donor units received by these patients contained detectable HBsAg. Of the 362 transfusion recipients, 23 (6%) developed 25 episodes of hepatitis; only 4 of these 25 episodes were serologically related to H.B.V. Based on the absence of antibody to HBsAg anti-HBs) prior to transfusion, 278 of the patients were considered susceptible to H.B.V. infection. Of these susceptible patients, 133 received at least one unit of blood containing anti-HBs; when compared with the 145 who did not receive anti-HBs, there was no significant difference in biochemical or overt hepatitis B (3/133 vs. 1/145), in serological response to H.B.V. 5/133 vs. 5/145), or in hepatitis unrelated to H.B.V. 11/133 vs. 6/145). It is concluded that blood containing detectable anti-HBs carries no increased risk of transmitting hepatitis B compared with blood which lacks this antibody." @default.
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- W2051226166 date "1974-07-01" @default.
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- W2051226166 title "RISK OF TRANSFUSING BLOOD CONTAINING ANTIBODY TO HEPATITIS-B SURFACE ANTIGEN" @default.
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- W2051226166 doi "https://doi.org/10.1016/s0140-6736(74)91485-8" @default.
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