FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051226757> ?p ?o ?g. }

• W2051226757 endingPage "1190" @default.
• W2051226757 startingPage "1186" @default.
• W2051226757 abstract "Selenium(Se)-enriched green tea consumption in human diets is well-known to reduce the risk of a variety of diseases. Here, we isolated a Se-polysaccharide (Se-ZYTP) from Se-enriched Ziyang green tea and investigated its antitumor activity on human osteosarcoma U-2 OS cells in vitro and in vivo. Se-ZYTP contained 94.5% of carbohydrate and 2.1% of uronic acid, as well as 2.14 μg/g Se, revealing that Se-ZYTP was an acidic Se-conjugated polysaccharide. Monosaccharide composition analysis indicated that Se-ZYTP consisted of mannose, rhamnose and fucose in molar ratios of 2.4:1.5:1.2:0.2:0.1:0.3:0.3. In vitro, both MTT and LTH assays proved that Se-ZYTP (25, 50, 100 and 200 μg/ml) could significantly inhibit the proliferation of human osteosarcoma U-2 OS cells in a concentration-dependent fashion (P < 0.05 or P < 0.01). In U-2 OS cancer xenograft model in BALB/c athymic mice, Se-ZYTP oral administration at three doses of 100, 200 and 400 mg/kg body weight (B.W.) daily for 28 days resulted in obvious tumor regression as compared to model control (P < 0.05 or P < 0.01). In addition, body weights of mice in control or Se-ZYTP treated groups did not differ significantly and no mice died during experiment, suggesting the safety of Se-ZYTP. Therefore, we postulate that Se-ZYTP might have cancer-preventive and cancer-therapeutic benefit for human osteosarcoma." @default.
• W2051226757 created "2016-06-24" @default.
• W2051226757 creator A5004846643 @default.
• W2051226757 creator A5004864878 @default.
• W2051226757 creator A5006919426 @default.
• W2051226757 creator A5034788355 @default.
• W2051226757 creator A5038008601 @default.
• W2051226757 creator A5054850777 @default.
• W2051226757 creator A5059667427 @default.
• W2051226757 date "2013-10-01" @default.
• W2051226757 modified "2023-09-22" @default.
• W2051226757 title "Tumoricidal effects of a selenium (Se)-polysaccharide from Ziyang green tea on human osteosarcoma U-2 OS cells" @default.
• W2051226757 cites W1968834637 @default.
• W2051226757 cites W1976701299 @default.
• W2051226757 cites W1991369749 @default.
• W2051226757 cites W1992372996 @default.
• W2051226757 cites W2000354575 @default.
• W2051226757 cites W2003853866 @default.
• W2051226757 cites W2010189469 @default.
• W2051226757 cites W2013115322 @default.
• W2051226757 cites W2013881151 @default.
• W2051226757 cites W2017731369 @default.
• W2051226757 cites W2020920713 @default.
• W2051226757 cites W2023372627 @default.
• W2051226757 cites W2029748021 @default.
• W2051226757 cites W2038314648 @default.
• W2051226757 cites W2050725703 @default.
• W2051226757 cites W2057128537 @default.
• W2051226757 cites W2066002973 @default.
• W2051226757 cites W2069615496 @default.
• W2051226757 cites W2072029917 @default.
• W2051226757 cites W2078421398 @default.
• W2051226757 cites W2087915587 @default.
• W2051226757 cites W2088796820 @default.
• W2051226757 cites W2103492103 @default.
• W2051226757 cites W2117165478 @default.
• W2051226757 cites W2134071616 @default.
• W2051226757 cites W2136725886 @default.
• W2051226757 cites W2150301699 @default.
• W2051226757 cites W2161030469 @default.
• W2051226757 cites W2163956097 @default.
• W2051226757 cites W2170942205 @default.
• W2051226757 cites W4293247451 @default.
• W2051226757 doi "https://doi.org/10.1016/j.carbpol.2013.07.022" @default.
• W2051226757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23987462" @default.
• W2051226757 hasPublicationYear "2013" @default.
• W2051226757 type Work @default.
• W2051226757 sameAs 2051226757 @default.
• W2051226757 citedByCount "70" @default.
• W2051226757 countsByYear W20512267572014 @default.
• W2051226757 countsByYear W20512267572015 @default.
• W2051226757 countsByYear W20512267572016 @default.
• W2051226757 countsByYear W20512267572017 @default.
• W2051226757 countsByYear W20512267572018 @default.
• W2051226757 countsByYear W20512267572019 @default.
• W2051226757 countsByYear W20512267572020 @default.
• W2051226757 countsByYear W20512267572021 @default.
• W2051226757 countsByYear W20512267572022 @default.
• W2051226757 countsByYear W20512267572023 @default.
• W2051226757 crossrefType "journal-article" @default.
• W2051226757 hasAuthorship W2051226757A5004846643 @default.
• W2051226757 hasAuthorship W2051226757A5004864878 @default.
• W2051226757 hasAuthorship W2051226757A5006919426 @default.
• W2051226757 hasAuthorship W2051226757A5034788355 @default.
• W2051226757 hasAuthorship W2051226757A5038008601 @default.
• W2051226757 hasAuthorship W2051226757A5054850777 @default.
• W2051226757 hasAuthorship W2051226757A5059667427 @default.
• W2051226757 hasConcept C100817775 @default.
• W2051226757 hasConcept C118859902 @default.
• W2051226757 hasConcept C150903083 @default.
• W2051226757 hasConcept C178790620 @default.
• W2051226757 hasConcept C185592680 @default.
• W2051226757 hasConcept C202751555 @default.
• W2051226757 hasConcept C207001950 @default.
• W2051226757 hasConcept C2776841590 @default.
• W2051226757 hasConcept C2777760704 @default.
• W2051226757 hasConcept C2778173381 @default.
• W2051226757 hasConcept C2778284416 @default.
• W2051226757 hasConcept C2779213145 @default.
• W2051226757 hasConcept C502942594 @default.
• W2051226757 hasConcept C553756173 @default.
• W2051226757 hasConcept C55493867 @default.
• W2051226757 hasConcept C71924100 @default.
• W2051226757 hasConcept C86803240 @default.
• W2051226757 hasConcept C98274493 @default.
• W2051226757 hasConceptScore W2051226757C100817775 @default.
• W2051226757 hasConceptScore W2051226757C118859902 @default.
• W2051226757 hasConceptScore W2051226757C150903083 @default.
• W2051226757 hasConceptScore W2051226757C178790620 @default.
• W2051226757 hasConceptScore W2051226757C185592680 @default.
• W2051226757 hasConceptScore W2051226757C202751555 @default.
• W2051226757 hasConceptScore W2051226757C207001950 @default.
• W2051226757 hasConceptScore W2051226757C2776841590 @default.
• W2051226757 hasConceptScore W2051226757C2777760704 @default.
• W2051226757 hasConceptScore W2051226757C2778173381 @default.
• W2051226757 hasConceptScore W2051226757C2778284416 @default.
• W2051226757 hasConceptScore W2051226757C2779213145 @default.
• W2051226757 hasConceptScore W2051226757C502942594 @default.

• next