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- W2051228317 abstract "The glucose and nitrogen starvation stimulons of Bacillus licheniformis were determined by transcriptome and proteome analyses. Under both starvation conditions, the main response of B. licheniformis was a switch to the usage of alternative nutrient sources. This was indicated by an induction of genes involved in the metabolism of C-2 substrates during glucose limitation. In addition, B. licheniformis seems to be using other organic substances like amino acids and lipids as carbon sources when subjected to glucose starvation. This observation is supported by the induction of a high number of genes coding for proteins involved in amino acid and lipid degradation. During nitrogen starvation, genes for several proteases and peptidases involved in nitrate and nitrite assimilation were induced, which enables this bacterium to recruit nitrogen from alternative sources. Both starvation conditions led to a down-regulation of transcription of most vegetative genes, which was subsequently reflected by a reduced synthesis of the corresponding proteins. A selected set of genes was induced by both starvation conditions. Among them were yvyD, citA and the putative methylcitrate shunt genes mmgD, mmgE and yqiQ. However, both starvation conditions did not induce a general SigmaB-dependent stress response." @default.
- W2051228317 created "2016-06-24" @default.
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- W2051228317 date "2007-02-01" @default.
- W2051228317 modified "2023-10-06" @default.
- W2051228317 title "The glucose and nitrogen starvation response ofBacillus licheniformis" @default.
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- W2051228317 doi "https://doi.org/10.1002/pmic.200600556" @default.
- W2051228317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17274076" @default.
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