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- W2051233147 abstract "The distribution of myomodulinlike immunoreactivity in the leech CNS was determined using an antiserum raised against Aplysia myomodulin. Segmental ganglia contained approximately 60 immunoreactive neurons. In addition, numerous fibers containing immunoreactive varicosities were found throughout the neuropil. Using a combination of Lucifer Yellow injections and immunocytochemistry, we identified neurons including the anterior Pagodas (AP), annulus erector (AE), motor neurons, Leydig, longitudinal muscle motoneurons (L), S cells, and coupling interneurons, all of which are active during the touch-elicited shortening reflex. FMRF-amide-like immunoreactivity in three of these cells (L, AP, and AE) was previously demonstrated. Specific staining for myomodulin was abolished by preadsorption of the antiserum with synthetic myomodulin, but not with FMRF-amide. These results suggest a potential role for myomodulin in both intrinsic and extrinsic modulation of the leech touch-elicited shortening reflex. Further, it is possible that several neurons mediating this reflex contain multiple neuromodulatory peptides." @default.
- W2051233147 created "2016-06-24" @default.
- W2051233147 creator A5045571992 @default.
- W2051233147 creator A5024502317 @default.
- W2051233147 date "1996-07-01" @default.
- W2051233147 modified "2023-10-15" @default.
- W2051233147 title "Localization of the myomodulin-like immunoreactivity in the leech CNS" @default.
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- W2051233147 doi "https://doi.org/10.1002/(sici)1097-4695(199607)30:3<374::aid-neu6>3.0.co;2-1" @default.
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