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- W2051233735 abstract "Phosphoinositide signalling regulates a series of important neuronal processes that are thought to be altered in mood disorders. Furthermore, mood-stabilizing drugs inhibit key enzymes that regulate phosphoinositide production and alter neuronal growth cone morphology in an inositol-reversible manner. Inositol is taken up by neurons from the extracellular fluid, presumably via membrane transporters; it can also be synthesized by the enzyme MIP-synthase (myo-inositol-1-phosphate synthase) and, in addition, it is generated by inositol phospholipid hydrolysis. The neuronal-specific HMIT (H(+)-myo-inositol transporter) represents a potential regulator of inositol signalling in neurons that warrants further investigation." @default.
- W2051233735 created "2016-06-24" @default.
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- W2051233735 date "2009-09-21" @default.
- W2051233735 modified "2023-10-16" @default.
- W2051233735 title "Investigation of the H+–<i>myo</i>-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling" @default.
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- W2051233735 doi "https://doi.org/10.1042/bst0371139" @default.
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