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• W2051233884 abstract "High-grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic carcinoma. PIN has a high predictive value as a marker for carcinoma, and its identification in biopsy specimens warrants repeat biopsy for concurrent or subsequent carcinoma. The only methods of detection are biopsy and transurethral resection; PIN does not significantly elevate serum PSA concentration or its derivatives, nor does it induce a palpable mass, and cannot be detected by ultrasound. Androgen deprivation therapy decreases the prevalence and extent of PIN, suggesting that this form of treatment may play a role in chemoprevention. Radiation therapy is also associated with a decreased incidence of PIN." @default.
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• W2051233884 date "2000-01-01" @default.
• W2051233884 modified "2023-09-27" @default.
• W2051233884 title "Diagnosis of Prostatic Intraepithelial Neoplasia: Prostate Working Group 1 Consensus Report" @default.
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• W2051233884 doi "https://doi.org/10.1080/003655900750169266" @default.
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