Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051234956> ?p ?o ?g. }
- W2051234956 abstract "Human cytomegalovirus (HCMV) is an important pathogen of viral pneumonia in children. The diagnosis of acute HCMV infection is complicated and difficult. Clinical and laboratory data of 6063 hospitalized children with respiratory infection and 509 with respiratory virus infection alone were retrospectively analyzed. Urine and respiratory specimens of 186 hospitalized children with pneumonia were also prospectively collected. Real-time polymerase chain reaction (PCR) and a chemiluminescent assay were used to detect HCMV DNA copy number, the pp65 gene, and HCMV IgM. The patients with respiratory virus infection alone and those with pulmonary HCMV infection (n = 422) were mostly children aged <6 months old (82.91%, 422/509). The accuracy of urine HCMV DNA (82.32%) was higher than that of HCMV IgM (67.78%), indicating that PCR of urine samples is suitable for determining pediatric acute pulmonary HCMV infection. There was no significant difference in detecting HCMV DNA or the pp65 gene between urinary and respiratory specimens (P > 0.05) in 186 pediatric pneumonia cases. The accuracy of the pp65 gene measured in urine for determining acute pulmonary HCMV infection was the highest (93.01%). Our study shows a novel method for investigating acute pulmonary HCMV infection in children by using real-time PCR and non-invasive samples. This study also highlights the superiority and potential use of the pp65 gene as an important target for the diagnosis of acute pulmonary HCMV infection." @default.
- W2051234956 created "2016-06-24" @default.
- W2051234956 creator A5013411080 @default.
- W2051234956 creator A5017238139 @default.
- W2051234956 creator A5017280793 @default.
- W2051234956 creator A5019471478 @default.
- W2051234956 creator A5021376490 @default.
- W2051234956 creator A5036316633 @default.
- W2051234956 creator A5068204719 @default.
- W2051234956 creator A5075240056 @default.
- W2051234956 creator A5075920939 @default.
- W2051234956 creator A5082577432 @default.
- W2051234956 creator A5083967189 @default.
- W2051234956 creator A5091895604 @default.
- W2051234956 date "2014-05-08" @default.
- W2051234956 modified "2023-10-14" @default.
- W2051234956 title "Urine real-time polymerase chain reaction detection for children virus pneumonia with acute human cytomegalovirus infection" @default.
- W2051234956 cites W1541506293 @default.
- W2051234956 cites W1585608323 @default.
- W2051234956 cites W1971918594 @default.
- W2051234956 cites W1984341857 @default.
- W2051234956 cites W1988715136 @default.
- W2051234956 cites W2004873852 @default.
- W2051234956 cites W2021761151 @default.
- W2051234956 cites W2032322989 @default.
- W2051234956 cites W2040477281 @default.
- W2051234956 cites W2083559826 @default.
- W2051234956 cites W2096002663 @default.
- W2051234956 cites W2096233660 @default.
- W2051234956 cites W2099134729 @default.
- W2051234956 cites W2116003094 @default.
- W2051234956 cites W2128592628 @default.
- W2051234956 cites W2129130306 @default.
- W2051234956 cites W2131678022 @default.
- W2051234956 cites W2152293766 @default.
- W2051234956 cites W2154822979 @default.
- W2051234956 cites W2155061295 @default.
- W2051234956 cites W2327938784 @default.
- W2051234956 doi "https://doi.org/10.1186/1471-2334-14-245" @default.
- W2051234956 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4024271" @default.
- W2051234956 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24884393" @default.
- W2051234956 hasPublicationYear "2014" @default.
- W2051234956 type Work @default.
- W2051234956 sameAs 2051234956 @default.
- W2051234956 citedByCount "8" @default.
- W2051234956 countsByYear W20512349562016 @default.
- W2051234956 countsByYear W20512349562017 @default.
- W2051234956 countsByYear W20512349562019 @default.
- W2051234956 countsByYear W20512349562020 @default.
- W2051234956 countsByYear W20512349562023 @default.
- W2051234956 crossrefType "journal-article" @default.
- W2051234956 hasAuthorship W2051234956A5013411080 @default.
- W2051234956 hasAuthorship W2051234956A5017238139 @default.
- W2051234956 hasAuthorship W2051234956A5017280793 @default.
- W2051234956 hasAuthorship W2051234956A5019471478 @default.
- W2051234956 hasAuthorship W2051234956A5021376490 @default.
- W2051234956 hasAuthorship W2051234956A5036316633 @default.
- W2051234956 hasAuthorship W2051234956A5068204719 @default.
- W2051234956 hasAuthorship W2051234956A5075240056 @default.
- W2051234956 hasAuthorship W2051234956A5075920939 @default.
- W2051234956 hasAuthorship W2051234956A5082577432 @default.
- W2051234956 hasAuthorship W2051234956A5083967189 @default.
- W2051234956 hasAuthorship W2051234956A5091895604 @default.
- W2051234956 hasBestOaLocation W20512349561 @default.
- W2051234956 hasConcept C104317684 @default.
- W2051234956 hasConcept C126322002 @default.
- W2051234956 hasConcept C159047783 @default.
- W2051234956 hasConcept C190139176 @default.
- W2051234956 hasConcept C203014093 @default.
- W2051234956 hasConcept C2522874641 @default.
- W2051234956 hasConcept C2776178081 @default.
- W2051234956 hasConcept C2776409557 @default.
- W2051234956 hasConcept C2777662283 @default.
- W2051234956 hasConcept C2777714996 @default.
- W2051234956 hasConcept C2777732132 @default.
- W2051234956 hasConcept C2777914695 @default.
- W2051234956 hasConcept C2779820661 @default.
- W2051234956 hasConcept C2780026642 @default.
- W2051234956 hasConcept C2780727368 @default.
- W2051234956 hasConcept C2993183539 @default.
- W2051234956 hasConcept C48023723 @default.
- W2051234956 hasConcept C49105822 @default.
- W2051234956 hasConcept C534529494 @default.
- W2051234956 hasConcept C55493867 @default.
- W2051234956 hasConcept C71924100 @default.
- W2051234956 hasConcept C86803240 @default.
- W2051234956 hasConceptScore W2051234956C104317684 @default.
- W2051234956 hasConceptScore W2051234956C126322002 @default.
- W2051234956 hasConceptScore W2051234956C159047783 @default.
- W2051234956 hasConceptScore W2051234956C190139176 @default.
- W2051234956 hasConceptScore W2051234956C203014093 @default.
- W2051234956 hasConceptScore W2051234956C2522874641 @default.
- W2051234956 hasConceptScore W2051234956C2776178081 @default.
- W2051234956 hasConceptScore W2051234956C2776409557 @default.
- W2051234956 hasConceptScore W2051234956C2777662283 @default.
- W2051234956 hasConceptScore W2051234956C2777714996 @default.
- W2051234956 hasConceptScore W2051234956C2777732132 @default.
- W2051234956 hasConceptScore W2051234956C2777914695 @default.
- W2051234956 hasConceptScore W2051234956C2779820661 @default.
- W2051234956 hasConceptScore W2051234956C2780026642 @default.