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- W2051235518 abstract "A new method for the synthesis of 15N-labeled chiral β-diamines from a common precursor, either optically pure amino acids or anti-β-amino alcohols, is reported. The two diastereomeric series of vicinal diamines are produced through the nucleophilic ring opening of activated chiral aziridines. 15N was introduced by means of [15N]-benzylamine, prepared from 15NH4Cl. The final compounds are highly valuable because [1H–15N] NMR is considered a powerful tool for studying the chemical properties of platinum-based complexes." @default.
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- W2051235518 date "2013-02-01" @default.
- W2051235518 modified "2023-10-13" @default.
- W2051235518 title "Synthesis of 15N-labeled vicinal diamines through N-activated chiral aziridines: tools for the NMR study of platinum-based anticancer compounds" @default.
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- W2051235518 doi "https://doi.org/10.1016/j.tetlet.2012.11.079" @default.
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