Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051249692> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2051249692 abstract "We evaluated the stimulation of Chinese hamster ovary cells expressing human thyrotropin receptors (CHO-hTSHR cell) by sera of five patients with hydatidiform mole before and after the evacuation of the mole, and compared the results with serum human chorionic gonadotropin (hCG) concentrations and serum free thyroid hormones in these patients. Significantly increased CHO-hTSHR cell stimulating activities were observed in sera from untreated patients, and the activity decreased promptly after the evacuation of the mole, concomitantly with the decrease in serum hCG and free thyroid hormones. CHO-hTSHR cell stimulating activity of sera of the untreated patients significantly correlated with serum hCG. Moreover, serum hCG stimulated CHO-hTSHR cells in a dose dependent manner similar to the dose-response curve of the stimulation by purified hCG. Sera of the patients and purified hCG did not stimulate nontransfected CHO-K1 cells. However, a significant correlation was not observed between serum-free thyroid hormones and serum hCG or between serum free thyroid hormones and CHO-hTSHR cell stimulating activities in untreated patients. These results indicate that serum hCG from patients with hydatidiform mole stimulates thyroid gland by interacting with TSH receptors, and suggest that the increase in thyroid hormones in patients may depend on both the increased serum hCG and the responsiveness of their thyroid glands to hCG." @default.
- W2051249692 created "2016-06-24" @default.
- W2051249692 creator A5006529445 @default.
- W2051249692 creator A5052490297 @default.
- W2051249692 creator A5067531310 @default.
- W2051249692 creator A5072924443 @default.
- W2051249692 creator A5084855432 @default.
- W2051249692 creator A5085828129 @default.
- W2051249692 creator A5091627597 @default.
- W2051249692 date "1999-12-01" @default.
- W2051249692 modified "2023-09-27" @default.
- W2051249692 title "Stimulation of Chinese Hamster Ovary Cells Expressing Human Thyrotropin Receptors by Serum Human Chorionic Gonadotropin of Patients with Hydatidiform Mole" @default.
- W2051249692 cites W1966825113 @default.
- W2051249692 cites W1967375819 @default.
- W2051249692 cites W1989607389 @default.
- W2051249692 cites W2014379985 @default.
- W2051249692 cites W2031192188 @default.
- W2051249692 cites W2053283704 @default.
- W2051249692 cites W2069159786 @default.
- W2051249692 cites W2083034149 @default.
- W2051249692 cites W2095352289 @default.
- W2051249692 cites W2099784786 @default.
- W2051249692 cites W2105451065 @default.
- W2051249692 doi "https://doi.org/10.1089/thy.1999.9.1205" @default.
- W2051249692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10646659" @default.
- W2051249692 hasPublicationYear "1999" @default.
- W2051249692 type Work @default.
- W2051249692 sameAs 2051249692 @default.
- W2051249692 citedByCount "5" @default.
- W2051249692 crossrefType "journal-article" @default.
- W2051249692 hasAuthorship W2051249692A5006529445 @default.
- W2051249692 hasAuthorship W2051249692A5052490297 @default.
- W2051249692 hasAuthorship W2051249692A5067531310 @default.
- W2051249692 hasAuthorship W2051249692A5072924443 @default.
- W2051249692 hasAuthorship W2051249692A5084855432 @default.
- W2051249692 hasAuthorship W2051249692A5085828129 @default.
- W2051249692 hasAuthorship W2051249692A5091627597 @default.
- W2051249692 hasConcept C124815738 @default.
- W2051249692 hasConcept C126322002 @default.
- W2051249692 hasConcept C134018914 @default.
- W2051249692 hasConcept C16685009 @default.
- W2051249692 hasConcept C170493617 @default.
- W2051249692 hasConcept C175656101 @default.
- W2051249692 hasConcept C24998067 @default.
- W2051249692 hasConcept C2775948956 @default.
- W2051249692 hasConcept C2778324911 @default.
- W2051249692 hasConcept C2778362869 @default.
- W2051249692 hasConcept C2778575167 @default.
- W2051249692 hasConcept C2778782382 @default.
- W2051249692 hasConcept C71315377 @default.
- W2051249692 hasConcept C71924100 @default.
- W2051249692 hasConcept C86803240 @default.
- W2051249692 hasConceptScore W2051249692C124815738 @default.
- W2051249692 hasConceptScore W2051249692C126322002 @default.
- W2051249692 hasConceptScore W2051249692C134018914 @default.
- W2051249692 hasConceptScore W2051249692C16685009 @default.
- W2051249692 hasConceptScore W2051249692C170493617 @default.
- W2051249692 hasConceptScore W2051249692C175656101 @default.
- W2051249692 hasConceptScore W2051249692C24998067 @default.
- W2051249692 hasConceptScore W2051249692C2775948956 @default.
- W2051249692 hasConceptScore W2051249692C2778324911 @default.
- W2051249692 hasConceptScore W2051249692C2778362869 @default.
- W2051249692 hasConceptScore W2051249692C2778575167 @default.
- W2051249692 hasConceptScore W2051249692C2778782382 @default.
- W2051249692 hasConceptScore W2051249692C71315377 @default.
- W2051249692 hasConceptScore W2051249692C71924100 @default.
- W2051249692 hasConceptScore W2051249692C86803240 @default.
- W2051249692 hasLocation W20512496921 @default.
- W2051249692 hasLocation W20512496922 @default.
- W2051249692 hasOpenAccess W2051249692 @default.
- W2051249692 hasPrimaryLocation W20512496921 @default.
- W2051249692 hasRelatedWork W123930651 @default.
- W2051249692 hasRelatedWork W1971164848 @default.
- W2051249692 hasRelatedWork W1974313609 @default.
- W2051249692 hasRelatedWork W1988856329 @default.
- W2051249692 hasRelatedWork W1999422125 @default.
- W2051249692 hasRelatedWork W2019005474 @default.
- W2051249692 hasRelatedWork W2019089889 @default.
- W2051249692 hasRelatedWork W2024342311 @default.
- W2051249692 hasRelatedWork W2058888093 @default.
- W2051249692 hasRelatedWork W2065357384 @default.
- W2051249692 hasRelatedWork W2090541153 @default.
- W2051249692 hasRelatedWork W2092021870 @default.
- W2051249692 hasRelatedWork W2120307987 @default.
- W2051249692 hasRelatedWork W2157735058 @default.
- W2051249692 hasRelatedWork W2273980284 @default.
- W2051249692 hasRelatedWork W2321476422 @default.
- W2051249692 hasRelatedWork W2415011447 @default.
- W2051249692 hasRelatedWork W2416870206 @default.
- W2051249692 hasRelatedWork W2432170808 @default.
- W2051249692 hasRelatedWork W382517207 @default.
- W2051249692 isParatext "false" @default.
- W2051249692 isRetracted "false" @default.
- W2051249692 magId "2051249692" @default.
- W2051249692 workType "article" @default.